Literature DB >> 26306308

Role of Fine Needle Aspiration Cytology (FNAC) as a Diagnostic Tool in Paediatric Head and Neck Lymphodenopathy.

O A Silas1, O O Ige2, A A Adoga3, L T Nimkur3, O I Ajetunmobi1.   

Abstract

A neck mass that is present for longer than a week might be pathological requiring rapid and thorough evaluation. This study aims to evaluate the positive role Fine needle aspiration cytology plays in the diagnosis of pediatric patients with lymphadenopathy in the head and neck region. Fine needle aspiration of lymph nodes was carried out, fixed and stained by cytopathologists for 56 patients at the Jos University Teaching Hospital, 43 (76.8%) were inflammatory and 13 (23.2%) malignant. Reactive hyperplasia (72.1%), acute suppurative (18.6%) and tuberculosis (9.3%) constituted the inflammatory lesions. Non Hodgkins lymphoma was the commonest malignant lesion (76.9%) followed by Hodgkins lymphoma (15.4%), the least being Rhabdomyosarcoma (7.7%). Age range 10-14 years had the highest number of cases (46.4%). Males were 36 (64.3%) while females were 20 (35.7%). All malignant cases diagnosed by FNAC had to undergo confirmation/characterization by histology and had 100% concordance. Thus there were no false positives and specificity was 100%, sensitivity 100%. Of the 43 diagnosed as inflammatory by FNAC, 12 cases which did not resolve after treatment or where patients condition worsened had to undergo surgical biopsy. Out of these only 1 (8.3%) case of fungal infection was misdiagnosed by FNAC. The lymph nodes were generalized 4 (7.1%) and localized in 52 (92.9%). Maximum number of cases 53 (94.6%) had Cervical Lymphadenopathy followed by axillary 2 (3.6%) and inguinal 1 (1.8%). Out of the cervical group of nodes, the upper anterior and upper posterior deep cervical nodes were involved in majority of cases (95%).

Entities:  

Keywords:  Fine needle aspiration cytology; Jos University Teaching Hospital; Lymphadenopathy; Pediatrics

Year:  2015        PMID: 26306308      PMCID: PMC4543318          DOI: 10.4172/2324-8785.1000211

Source DB:  PubMed          Journal:  J Otol Rhinol        ISSN: 2324-8785


  10 in total

1.  FNAC as a diagnostic tool in pediatric head and neck lesions.

Authors:  M Jain; D D Majumdar; K Agarwal; A S Bais; M Choudhury
Journal:  Indian Pediatr       Date:  1999-09       Impact factor: 1.411

2.  Fine needle aspiration cytology of head and neck masses.

Authors:  Vijay Tilak; A V Dhaded; Ragini Jain
Journal:  Indian J Pathol Microbiol       Date:  2002-01       Impact factor: 0.740

3.  Role of fine needle aspiration cytology in the diagnosis of palpable thyroid lesions.

Authors:  Nazma Afroze; Naila Kayani; Sheema H Hasan
Journal:  Indian J Pathol Microbiol       Date:  2002-07       Impact factor: 0.740

4.  Spectrum of cytological findings in patients with neck lymphadenopathy--experience in a tertiary care hospital in Pakistan.

Authors:  Saira Fatima; Sidra Arshad; Zubair Ahmed; Sheema H Hasan
Journal:  Asian Pac J Cancer Prev       Date:  2011

Review 5.  Enlarged neck lymph nodes in children.

Authors:  Karthik Rajasekaran; Paul Krakovitz
Journal:  Pediatr Clin North Am       Date:  2013-07-03       Impact factor: 3.278

6.  Sensitivity of cytology in the diagnosis of paediatric malignancies in Nigeria.

Authors:  Akinfenwa T Atanda; Umar A Shehu
Journal:  J Trop Pediatr       Date:  2011-01-21       Impact factor: 1.165

7.  Fine-needle aspiration cytology in the diagnosis of superficial lymphadenopathy: an analysis of 2,418 cases.

Authors:  R R Prasad; R Narasimhan; V Sankaran; A J Veliath
Journal:  Diagn Cytopathol       Date:  1996-12       Impact factor: 1.582

8.  A preliminary report of fine-needle aspiration biopsy in superficially accessible lesions in children.

Authors:  A M O Shonubi; O Akiode; B A Salami; A A Musa; L M Ntele
Journal:  West Afr J Med       Date:  2004 Jul-Sep

9.  Review of fine needle aspiration cytology in the management of goitres in Ibadan, Nigeria.

Authors:  A O Afolabi; A O Oluwasola; O O Akute; E E U Akang; T O Ogundiran; J O Ogunbiyi; D O Irabor
Journal:  Niger J Clin Pract       Date:  2010-06       Impact factor: 0.968

10.  A review of the utilization of fine needle aspiration in clinical practice and research in Nigeria.

Authors:  Sani Abubakar Malami; Ochicha Ochicha
Journal:  Cytojournal       Date:  2011-06-23       Impact factor: 2.091

  10 in total
  2 in total

1.  Histological Surprises in Benign Cytologies after Lymph Node Biopsy-Surgeon's Knife Improving Patient Care.

Authors:  Mario Victor Newton; Rakesh S Ramesh; Suraj Manjunath; K ShivaKumar; Hemanth G Nanjappa; Ramu Damuluri; Elvis Peter Joseph; C Prasad
Journal:  Indian J Surg Oncol       Date:  2016-11-29

2.  Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report.

Authors:  Huan Wang; Lian-Nv Qiu; Mao Wu; Wan-Yuan Chen; Li-Gang Ren; Xiang-Lei He; Yong-Lie Zhou
Journal:  Oncol Lett       Date:  2016-02-25       Impact factor: 2.967

  2 in total

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