| Literature DB >> 26305590 |
Abstract
Cells that undergo epithelial-to-mesenchymal transitions (EMTs) commonly switch from expressing E-cadherin to N-cadherin. But why this occurs is not well understood. In the current issue of Developmental Cell, Scarpa et al. (2015) identify a reason: cadherin switching controls Rac signaling to determine how cell locomotion is regulated by contact.Entities:
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Year: 2015 PMID： 26305590 DOI： 10.1016/j.devcel.2015.08.002
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270