Literature DB >> 26304816

Cryptosporidium: a first step toward tractability.

Lizbeth Hedstrom1.   

Abstract

The child-killer and famously recalcitrant parasite Cryptosporidium is the latest organism to yield to the magic of CRISPR/Cas9. The ability to knockout genes and introduce markers promises a new heyday for drug discovery and vaccine development as well as the basic biology of these fascinating parasites.
Copyright © 2015. Published by Elsevier Ltd.

Entities:  

Keywords:  CRISPR/Cas9; gene knockout; reporter parasites; target validation

Mesh：

Year:  2015        PMID： 26304816      PMCID： PMC4568825          DOI： 10.1016/j.pt.2015.08.003

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  10 in total

Review 1.  A hundred-year retrospective on cryptosporidiosis.

Authors:  Saul Tzipori; Giovanni Widmer
Journal:  Trends Parasitol       Date:  2008-03-07

2.  Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis.

Authors:  Suresh Kumar Gorla; Nina N McNair; Guangyi Yang; Song Gao; Ming Hu; Venkatakrishna R Jala; Bodduluri Haribabu; Boris Striepen; Gregory D Cuny; Jan R Mead; Lizbeth Hedstrom
Journal:  Antimicrob Agents Chemother       Date:  2013-12-23       Impact factor: 5.191

3.  Parasitic infections: Time to tackle cryptosporidiosis.

Authors:  Boris Striepen
Journal:  Nature       Date:  2013-11-14       Impact factor: 49.962

Review 4.  A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium.

Authors:  William Checkley; A Clinton White; Devan Jaganath; Michael J Arrowood; Rachel M Chalmers; Xian-Ming Chen; Ronald Fayer; Jeffrey K Griffiths; Richard L Guerrant; Lizbeth Hedstrom; Christopher D Huston; Karen L Kotloff; Gagandeep Kang; Jan R Mead; Mark Miller; William A Petri; Jeffrey W Priest; David S Roos; Boris Striepen; R C Andrew Thompson; Honorine D Ward; Wesley A Van Voorhis; Lihua Xiao; Guan Zhu; Eric R Houpt
Journal:  Lancet Infect Dis       Date:  2014-09-29       Impact factor: 25.071

5.  The genome of Cryptosporidium hominis.

Authors:  Ping Xu; Giovanni Widmer; Yingping Wang; Luiz S Ozaki; Joao M Alves; Myrna G Serrano; Daniela Puiu; Patricio Manque; Donna Akiyoshi; Aaron J Mackey; William R Pearson; Paul H Dear; Alan T Bankier; Darrell L Peterson; Mitchell S Abrahamsen; Vivek Kapur; Saul Tzipori; Gregory A Buck
Journal:  Nature       Date:  2004-10-28       Impact factor: 49.962

6.  Gene transfer in the evolution of parasite nucleotide biosynthesis.

Authors:  Boris Striepen; Andrea J P Pruijssers; Jinling Huang; Catherine Li; Marc-Jan Gubbels; Nwakaso N Umejiego; Lizbeth Hedstrom; Jessica C Kissinger
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-18       Impact factor: 11.205

7.  Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.

Authors:  Karen L Kotloff; James P Nataro; William C Blackwelder; Dilruba Nasrin; Tamer H Farag; Sandra Panchalingam; Yukun Wu; Samba O Sow; Dipika Sur; Robert F Breiman; Abu Sg Faruque; Anita Km Zaidi; Debasish Saha; Pedro L Alonso; Boubou Tamboura; Doh Sanogo; Uma Onwuchekwa; Byomkesh Manna; Thandavarayan Ramamurthy; Suman Kanungo; John B Ochieng; Richard Omore; Joseph O Oundo; Anowar Hossain; Sumon K Das; Shahnawaz Ahmed; Shahida Qureshi; Farheen Quadri; Richard A Adegbola; Martin Antonio; M Jahangir Hossain; Adebayo Akinsola; Inacio Mandomando; Tacilta Nhampossa; Sozinho Acácio; Kousick Biswas; Ciara E O'Reilly; Eric D Mintz; Lynette Y Berkeley; Khitam Muhsen; Halvor Sommerfelt; Roy M Robins-Browne; Myron M Levine
Journal:  Lancet       Date:  2013-05-14       Impact factor: 79.321

8.  Complete genome sequence of the apicomplexan, Cryptosporidium parvum.

Authors:  Mitchell S Abrahamsen; Thomas J Templeton; Shinichiro Enomoto; Juan E Abrahante; Guan Zhu; Cheryl A Lancto; Mingqi Deng; Chang Liu; Giovanni Widmer; Saul Tzipori; Gregory A Buck; Ping Xu; Alan T Bankier; Paul H Dear; Bernard A Konfortov; Helen F Spriggs; Lakshminarayan Iyer; Vivek Anantharaman; L Aravind; Vivek Kapur
Journal:  Science       Date:  2004-03-25       Impact factor: 47.728

9.  Outbreaks of Illness Associated with Recreational Water--United States, 2011-2012.

Authors:  Michele C Hlavsa; Virginia A Roberts; Amy M Kahler; Elizabeth D Hilborn; Taryn R Mecher; Michael J Beach; Timothy J Wade; Jonathan S Yoder
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2015-06-26       Impact factor: 17.586

10.  Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum.

Authors:  Sumiti Vinayak; Mattie C Pawlowic; Adam Sateriale; Carrie F Brooks; Caleb J Studstill; Yael Bar-Peled; Michael J Cipriano; Boris Striepen
Journal:  Nature       Date:  2015-07-15       Impact factor: 49.962
  10 in total
  3 in total

Review 1.  Recent advances in genetic manipulation of Cryptosporidium.

Authors:  Sumiti Vinayak
Journal:  Curr Opin Microbiol       Date:  2020-11-05       Impact factor: 7.934

Review 2.  Recent Breakthroughs and Ongoing Limitations in Cryptosporidium Research.

Authors:  Seema Bhalchandra; Daviel Cardenas; Honorine D Ward
Journal:  F1000Res       Date:  2018-09-03

3.  Metabolic Signatures of Cryptosporidiumzzm321990 parvum-Infected HCT-8 Cells and Impact of Selected Metabolic Inhibitors on C. parvum Infection under Physioxia and Hyperoxia.

Authors:  Juan Vélez; Zahady Velasquez; Liliana M R Silva; Ulrich Gärtner; Klaus Failing; Arwid Daugschies; Sybille Mazurek; Carlos Hermosilla; Anja Taubert
Journal:  Biology (Basel)       Date:  2021-01-15
  3 in total

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