| Literature DB >> 26304428 |
Jelena D Nađpal1, Marija M Lesjak1, Filip S Šibul1, Goran T Anačkov2, Dragana D Četojević-Simin3, Neda M Mimica-Dukić1, Ivana N Beara4.
Abstract
The aim of this study was to compare phenolic profile, vitamin C content, antioxidant, anti-inflammatory and cytotoxic activity of rose hips and the preserves (purée and jam) of two Rosa species: renowned Rosa canina L. and unexplored Rosa arvensis Huds. The liquid chromatography-tandem mass spectrometry analysis of 45 phenolics resulted in quantification of 14 compounds, with quercitrin, gallic and protocatechuic acids as the most dominant. High antioxidant potential of R. canina and a moderate activity of R. arvensis extracts were determined through several assays. Purée of both species and methanol extract of air-dried R. canina hips showed some anti-inflammatory (cyclooxygenase-1 and 12-lipooxygense inhibition potency) activity. Purée of R. canina exerted cytotoxic activity only against the HeLa cell line among several others (HeLa, MCF7, HT-29 and MRC-5). The presented results support traditional use of rose hips and their fruit preserves as food with health and nutritional benefits.Entities:
Keywords: Anti-inflammatory activity; Antioxidant activity; Cytotoxic activity; LC–MS/MS; Rosa arvensis Huds.; Rosa canina L.
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Year: 2015 PMID： 26304428 DOI： 10.1016/j.foodchem.2015.07.089
Source DB: PubMed Journal: Food Chem ISSN： 0308-8146 Impact factor: 7.514