The flash stimulated VEP in the diagnosis of glaucoma.

The Visual Evoked Potential using pattern stimulation has been used in recent years as an attempt to make an early diagnosis of glaucoma. However because of the macular dominance of responses obtained by this method, only diseases involving the papillomacular bundle reveal abnormality; such conditions do not occur in glaucoma. In this study we report the use of the early component (P1) of the flash stimulated visual evoked potential in the diagnosis of primary open angle glaucoma. It appears to provide an objective, accurate and repeatable screening technique. The size of P1 correlates well with the size of optic disc cupping, and field loss. The relationships between systemic vascular disease, P1 reductions, and glaucoma, lend support to the ischaemic origins of the disease.