Yong Li1, Muyan Li2, Qun Lv3, Guoli Chen4, Jingwen Chen1, Shaojun Li1, Yuhuan Mo1, Shiyan Ou1, Zongxiang Yuan1, Guodong Lu1, Yueming Jiang5. 1. Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China. 2. Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China. 3. Maternity and Child Care Health Hospital of Guangxi, Nanning, Guangxi, China. 4. Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. 5. Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China. Electronic address: ymjianggxmu@163.com.
Abstract
OBJECTIVES: The aim of this study was to investigate blood lead level and its relationship to essential elements (zinc, copper, iron, calcium and magnesium) in school-age children from Nanning, China. METHODS: A total of 2457 children aged from 6 to 14 years were enrolled in Nanning, China. The levels of lead (Pb), zinc (Zn), copper (Cu), iron (Fe), calcium (Ca) and magnesium (Mg) were determined by an atomic absorption spectrometer. RESULTS: The mean blood lead level (BLL) was 57.21±35.00μg/L. 188 (7.65%) asymptomatic children had toxic lead level higher than 100μg/L. The school-age boys had similar lead level among different age groups, while the elder girls had less BLL. The blood Zn and Fe were found to be increased in the boys with elevated BLL, but similar trends were not observed in the girls. Positive correlations between Pb and Fe or Mg (r=0.112, 0.062, respectively, p<0.01) and a negative correlation between Pb and Ca (r=-0.047, p<0.05) were further established in the studied children. CONCLUSIONS: Lead exposure in school-age children was still prevalent in Nanning. The boys and girls differed in blood levels of lead and other metallic elements. Lead exposure may induce metabolic disorder of other metallic elements in body.
OBJECTIVES: The aim of this study was to investigate blood lead level and its relationship to essential elements (zinc, copper, iron, calcium and magnesium) in school-age children from Nanning, China. METHODS: A total of 2457 children aged from 6 to 14 years were enrolled in Nanning, China. The levels of lead (Pb), zinc (Zn), copper (Cu), iron (Fe), calcium (Ca) and magnesium (Mg) were determined by an atomic absorption spectrometer. RESULTS: The mean blood lead level (BLL) was 57.21±35.00μg/L. 188 (7.65%) asymptomatic children had toxic lead level higher than 100μg/L. The school-age boys had similar lead level among different age groups, while the elder girls had less BLL. The blood Zn and Fe were found to be increased in the boys with elevated BLL, but similar trends were not observed in the girls. Positive correlations between Pb and Fe or Mg (r=0.112, 0.062, respectively, p<0.01) and a negative correlation between Pb and Ca (r=-0.047, p<0.05) were further established in the studied children. CONCLUSIONS: Lead exposure in school-age children was still prevalent in Nanning. The boys and girls differed in blood levels of lead and other metallic elements. Lead exposure may induce metabolic disorder of other metallic elements in body.
Authors: Qian Luo; Honglong Zhang; Haiping Wang; Li Ma; Min Huang; Jingping Niu; Bin Luo; Jun Yan; Xun Li Journal: Biol Trace Elem Res Date: 2021-10-28 Impact factor: 4.081
Authors: Shan Tan; Yang Yang; Zhiheng Chen; Lingling Zhao; Zuocheng Yang; Hongmei Dai; Wei He; Mei Jiang; Yanhua Yao; Ke Huang; Liu Li; Pengfei Zhu; Shasha Xu; Mingyi Zhao; Minghua Yang Journal: Front Public Health Date: 2022-04-18