Literature DB >> 26301703

Fertility Decision-Making Among Kenyan HIV-Serodiscordant Couples Who Recently Conceived: Implications for Safer Conception Planning.

Jillian Pintye1,2, Kenneth Ngure1,3, Kathryn Curran1, Sophie Vusha4, Nelly Mugo1,4, Connie Celum1,5,6, Jared M Baeten1,5,6, Renee Heffron1,6.   

Abstract

HIV-serodiscordant couples often choose to attempt pregnancy despite their HIV transmission risk. Optimizing delivery of HIV risk reduction strategies during peri-conception periods (i.e., safer conception) requires understanding how HIV-serodiscordant couples approach fertility decisions. We conducted 36 in-depth individual interviews with male and female partners of Kenyan heterosexual HIV-serodiscordant couples who recently conceived. Transcripts were analyzed by gender and HIV serostatus using open coding. Matrices were used to identify patterns and emerging themes. Most participants expressed acceptance of being in an HIV-serodiscordant couple and affirmed their resilience to live with serodiscordance and achieve their fertility goals. Overall, while the goal for childbearing was unchanged, conception became an urgent desire so that both partners could experience childrearing together while the HIV-infected partner was still healthy. Children also add value to the relationship, and multiple children were a commonly expressed desire. Couples' desires dominated those of individual partners in fertility decision-making, but male preferences were more influential when the individual desires differed. Values and preferences of the couple as a unit may mediate fertility decision-making in HIV-discordant couples. Thus, it is important that safer conception programs include both partners when appropriate and consider the relationship context during risk reduction counseling and when recommending risk reduction interventions.

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Year:  2015        PMID: 26301703      PMCID: PMC4553369          DOI: 10.1089/apc.2015.0063

Source DB:  PubMed          Journal:  AIDS Patient Care STDS        ISSN: 1087-2914            Impact factor:   5.078


  45 in total

Review 1.  Reproductive assistance in HIV serodiscordant couples.

Authors:  V Savasi; L Mandia; A Laoreti; I Cetin
Journal:  Hum Reprod Update       Date:  2012-11-11       Impact factor: 15.610

Review 2.  Antiretrovirals and safer conception for HIV-serodiscordant couples.

Authors:  Lynn T Matthews; Jennifer A Smit; Susan Cu-Uvin; Deborah Cohan
Journal:  Curr Opin HIV AIDS       Date:  2012-11       Impact factor: 4.283

3.  'He lacks his fatherhood': safer conception technologies and the biological imperative for fatherhood among recently-diagnosed Xhosa-speaking men living with HIV in South Africa.

Authors:  Tonya N Taylor; Joanne E Mantell; Ntobeko Nywagi; Nomazizi Cishe; Diane Cooper
Journal:  Cult Health Sex       Date:  2013-07-17

4.  Pre-exposure prophylaxis for conception (PrEP-C) as a risk reduction strategy in HIV-positive men and HIV-negative women in the UK.

Authors:  J Whetham; S Taylor; L Charlwood; T Keith; R Howell; C McInnes; E Payne; J Home; D White; Y Gilleece
Journal:  AIDS Care       Date:  2013-07-22

5.  A conceptual framework for understanding HIV risk behavior in the context of supporting fertility goals among HIV-serodiscordant couples.

Authors:  Tamaryn L Crankshaw; Lynn T Matthews; Janet Giddy; Angela Kaida; Norma C Ware; Jennifer A Smit; David R Bangsberg
Journal:  Reprod Health Matters       Date:  2012-12

Review 6.  Preconception care for people living with HIV: recommendations for advancing implementation.

Authors:  Riley J Steiner; Jacinda K Dariotis; Jean R Anderson; Sarah Finocchario-Kessler
Journal:  AIDS       Date:  2013-10       Impact factor: 4.177

Review 7.  Global policy review of antiretroviral therapy eligibility criteria for treatment and prevention of HIV and tuberculosis in adults, pregnant women, and serodiscordant couples.

Authors:  Somya Gupta; Reuben Granich; Amitabh B Suthar; Caoimhe Smyth; Rachel Baggaley; Delphine Sculier; Anand Date; Mitesh A Desai; Frank Lule; Elliot Raizes; Leopold Blanc; Gottfried Hirnschall
Journal:  J Acquir Immune Defic Syndr       Date:  2013-03-01       Impact factor: 3.731

8.  Reproductive decision-making and periconception practices among HIV-positive men and women attending HIV services in Durban, South Africa.

Authors:  Lynn T Matthews; Tamaryn Crankshaw; Janet Giddy; Angela Kaida; Jennifer A Smit; Norma C Ware; David R Bangsberg
Journal:  AIDS Behav       Date:  2013-02

Review 9.  Determinants of male involvement in maternal and child health services in sub-Saharan Africa: a review.

Authors:  John Ditekemena; Olivier Koole; Cyril Engmann; Richard Matendo; Antoinette Tshefu; Robert Ryder; Robert Colebunders
Journal:  Reprod Health       Date:  2012-11-21       Impact factor: 3.223

10.  Women's preferences regarding infant or maternal antiretroviral prophylaxis for prevention of mother-to-child transmission of HIV during breastfeeding and their views on Option B+ in Dar es Salaam, Tanzania.

Authors:  Matilda Ngarina; Edith A M Tarimo; Helga Naburi; Charles Kilewo; Mary Mwanyika-Sando; Guerino Chalamilla; Gunnel Biberfeld; Anna Mia Ekstrom
Journal:  PLoS One       Date:  2014-01-22       Impact factor: 3.240

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  19 in total

1.  Gendered differences in the perceived risks and benefits of oral PrEP among HIV-serodiscordant couples in Kenya.

Authors:  Jennifer J Carroll; Kenneth Ngure; Renee Heffron; Kathryn Curran; Nelly R Mugo; Jared M Baeten
Journal:  AIDS Care       Date:  2016-01-11

2.  Experiences Using Pre-Exposure Prophylaxis for Safer Conception Among HIV Serodiscordant Heterosexual Couples in the United States.

Authors:  Angela R Bazzi; Ashley A Leech; Dea L Biancarelli; Meg Sullivan; Mari-Lynn Drainoni
Journal:  AIDS Patient Care STDS       Date:  2017-07-18       Impact factor: 5.078

3.  Fertility desires and preferences for safer conception strategies among people receiving care for HIV at a publicly-funded clinic in Seattle, WA.

Authors:  Kerry A Thomson; Shireesha Dhanireddy; Michele Andrasik; Kerry Hancuch; Lindsay Legg; Jacob Keane-Candib; Renee Heffron
Journal:  AIDS Care       Date:  2017-10-25

4.  Experiences of HIV Positive Serostatus Disclosure to Sexual Partner Among Individuals in Discordant Couples in Mbarara City, Southwestern Uganda.

Authors:  Humphrey Atwijukiire; Gladys Nakidde; Anne Tweheyo Otwine; Jane Kabami
Journal:  HIV AIDS (Auckl)       Date:  2022-05-18

5.  Sexual and Relationship Benefits of a Safer Conception Intervention Among Men with HIV Who Seek to Have Children with Serodifferent Partners in Uganda.

Authors:  Amelia M Stanton; Mwebesa Bwana; Moran Owembabazi; Esther Atukunda; Elijah Musinguzi; Henrietta Ezegbe; Patricia Smith; Christina Psaros; Lynn T Matthews; Angela Kaida
Journal:  AIDS Behav       Date:  2021-11-19

6.  Fertility Intentions, Pregnancy, and Use of PrEP and ART for Safer Conception Among East African HIV Serodiscordant Couples.

Authors:  Renee Heffron; Kerry Thomson; Connie Celum; Jessica Haberer; Kenneth Ngure; Nelly Mugo; Elizabeth Bukusi; Elly Katabira; Josephine Odoyo; Nulu Bulya; Stephen Asiimwe; Edna Tindimwebwa; Jared M Baeten
Journal:  AIDS Behav       Date:  2018-06

7.  Safer conception among HIV-1 serodiscordant couples in East Africa: understanding knowledge, attitudes, and experiences.

Authors:  Kerry Hancuch; Jared Baeten; Kenneth Ngure; Connie Celum; Nelly Mugo; Edna Tindimwebwa; Renee Heffron
Journal:  AIDS Care       Date:  2018-02-17

8.  A Systematic Review of the Current Status of Safer Conception Strategies for HIV Affected Heterosexual Couples in Sub-Saharan Africa.

Authors:  D Joseph Davey; S West; V Umutoni; S Taleghani; H Klausner; E Farley; R Shah; S Madni; S Orewa; V Kottamasu; V Rice; Z Robbin; K M Wall
Journal:  AIDS Behav       Date:  2018-09

9.  I Knew I Would Be Safer. Experiences of Kenyan HIV Serodiscordant Couples Soon After Pre-Exposure Prophylaxis (PrEP) Initiation.

Authors:  Kenneth Ngure; Renee Heffron; Kathyrn Curran; Sophie Vusha; Mariah Ngutu; Nelly Mugo; Connie Celum; Jared M Baeten
Journal:  AIDS Patient Care STDS       Date:  2016-02       Impact factor: 5.078

10.  Counseling Framework for HIV-Serodiscordant Couples on the Integrated Use of Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention.

Authors:  Jennifer F Morton; Connie Celum; John Njoroge; Agnes Nakyanzi; Imeldah Wakhungu; Edna Tindimwebwa; Snaidah Ongachi; Eric Sedah; Emmanuel Okwero; Kenneth Ngure; Josephine Odoyo; Nulu Bulya; Jessica E Haberer; Jared M Baeten; Renee Heffron
Journal:  J Acquir Immune Defic Syndr       Date:  2017-01-01       Impact factor: 3.731

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