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Literature DB >> 26297228

Can ErbB2 overexpression protect against doxorubicin cardiotoxicity?

Petra Rocic¹.

Abstract

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2015 PMID： 26297228 PMCID： PMC4666963 DOI： 10.1152/ajpheart.00647.2015

Source DB: PubMed Journal: Am J Physiol Heart Circ Physiol ISSN： 0363-6135 Impact factor: 4.733

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Review 1. Oxidative stress and heart failure.

Authors: Hiroyuki Tsutsui; Shintaro Kinugawa; Shouji Matsushima
Journal: Am J Physiol Heart Circ Physiol Date: 2011-09-23 Impact factor: 4.733

2. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

Authors: D J Slamon; B Leyland-Jones; S Shak; H Fuchs; V Paton; A Bajamonde; T Fleming; W Eiermann; J Wolter; M Pegram; J Baselga; L Norton
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3. ErbB2 is essential in the prevention of dilated cardiomyopathy.

Authors: Steven A Crone; You-Yang Zhao; Lian Fan; Yusu Gu; Susumu Minamisawa; Yang Liu; Kirk L Peterson; Ju Chen; Ronald Kahn; Gianluigi Condorelli; John Ross; Kenneth R Chien; Kuo-Fee Lee
Journal: Nat Med Date: 2002-05 Impact factor: 53.440

4. Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation.

Authors: Heiko Bugger; Cinthia Guzman; Christoph Zechner; Monica Palmeri; Kerry S Russell; Raymond R Russell
Journal: Cancer Chemother Pharmacol Date: 2010-08-31 Impact factor: 3.333

Review 5. Cardiac toxicity of trastuzumab-related regimens in HER2-overexpressing breast cancer.

Authors: Michael S Ewer; Joyce A O'Shaughnessy
Journal: Clin Breast Cancer Date: 2007-06 Impact factor: 3.225

6. Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways.

Authors: Leo I Gordon; Michael A Burke; Amareshwar T K Singh; Sheila Prachand; Elliot D Lieberman; Lin Sun; Tejaswitha Jairaj Naik; Sathyamangla V Naga Prasad; Hossein Ardehali
Journal: J Biol Chem Date: 2008-11-18 Impact factor: 5.157

Can ErbB2 overexpression protect against doxorubicin cardiotoxicity?

Review 1. Oxidative stress and heart failure.

2. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

3. ErbB2 is essential in the prevention of dilated cardiomyopathy.

4. Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation.

Review 5. Cardiac toxicity of trastuzumab-related regimens in HER2-overexpressing breast cancer.

6. Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways.

7. Doxorubicin and trastuzumab regimen induces biventricular failure in mice.

8. Resolution of mitochondrial oxidative stress rescues coronary collateral growth in Zucker obese fatty rats.

9. Echocardiographic Detection of Cardiac Dysfunction in Childhood Cancer Survivors: How Long Is Screening Required?

10. Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics.