| Literature DB >> 26297206 |
Andriy Kuzmov1, Tamara Minko2.
Abstract
Local administration of therapeutics by inhalation for treatment of lung diseases has the ability to deliver drugs, nucleic acids and peptides specifically to the site of their action and therefore enhance the efficacy of the treatment, limit the penetration of nebulized therapeutic agent(s) into the bloodstream and consequently decrease adverse systemic side effects of the treatment. Nanotechnology allows for a further enhancement of the treatment efficiency. The present review analyzes modern therapeutic approaches of inhaled nanoscale-based pharmaceutics for the detection and treatment of various lung diseases.Entities:
Keywords: Fibrosis; Gene delivery; Hypoxia; Lung cancer; Nanoparticles; Pulmonary delivery
Mesh:
Substances:
Year: 2015 PMID: 26297206 DOI: 10.1016/j.jconrel.2015.07.024
Source DB: PubMed Journal: J Control Release ISSN: 0168-3659 Impact factor: 9.776