| Literature DB >> 26295959 |
Tobias P Dick1, Markus Ralser2.
Abstract
A sudden increase in pentose phosphate pathway (PPP) activity, the fastest known cellular response to oxidative stress, protects cells through timely generation of NADPH. Originally discovered in budding yeast, Kuehne and colleagues demonstrate the conservation of this mechanism in human cells and reveal its importance for skin cells exposed to UV light.Entities:
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Year: 2015 PMID： 26295959 DOI： 10.1016/j.molcel.2015.08.002
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970