Literature DB >> 26291628

Self-Reported Traumatic Brain Injury, Health and Rate of Chronic Multisymptom Illness in Veterans From the 1990-1991 Gulf War.

Megan K Yee1, Daniel R Seichepine, Patricia A Janulewicz, Kimberly A Sullivan, Susan P Proctor, Maxine H Krengel.   

Abstract

BACKGROUND: Traumatic brain injury (TBI) was not considered to be common in the 1990-1991 Gulf War (GW). Therefore, the relationship between TBI and chronic health symptoms experienced by GW veterans is unknown. Health symptoms reported by veterans deployed more recently to this region (Operations Enduring and Iraqi Freedom) are similar to those of GW veterans and have been primarily attributed to TBI.
OBJECTIVE: To examine the relationships among self-reported TBI, health symptoms, chronic multisymptom illness (CMI), and health-related quality of life among GW veterans. PARTICIPANTS: Participants included 1 274 GW veterans from the Devens Cohort Study, 156 of whom self-reported a history of TBI (12.2% of the sample).
DESIGN: Cross-sectional retrospective analysis of existing survey data. MAIN MEASURES: A 52-item health symptom checklist and the RAND 36-Item Health short Form Survey.
RESULTS: Self-reported TBI in GW Veterans is related to increased rates of health symptoms, CMI, and poorer health-related quality of life.
CONCLUSIONS: Gulf War veterans' self-reported exposure to TBI is related to increased rates of chronic health symptoms and CMI, which interfere with everyday activities of daily living.

Entities:  

Mesh:

Year:  2016        PMID: 26291628     DOI: 10.1097/HTR.0000000000000173

Source DB:  PubMed          Journal:  J Head Trauma Rehabil        ISSN: 0885-9701            Impact factor:   2.710


  11 in total

1.  Impact of gulf war toxic exposures after mild traumatic brain injury.

Authors:  Scott Ferguson; Robyn McCartan; Mackenzie Browning; Coral Hahn-Townsend; Arissa Gratkowski; Alexander Morin; Laila Abdullah; Ghania Ait-Ghezala; Joseph Ojo; Kimberly Sullivan; Michael Mullan; Fiona Crawford; Benoit Mouzon
Journal:  Acta Neuropathol Commun       Date:  2022-10-18       Impact factor: 7.578

2.  Alterations in high-order diffusion imaging in veterans with Gulf War Illness is associated with chemical weapons exposure and mild traumatic brain injury.

Authors:  Chia-Hsin Cheng; Bang-Bon Koo; Samantha Calderazzo; Emily Quinn; Kristina Aenlle; Lea Steele; Nancy Klimas; Maxine Krengel; Patricia Janulewicz; Rosemary Toomey; Lindsay T Michalovicz; Kimberly A Kelly; Timothy Heeren; Deborah Little; James P O'Callaghan; Kimberly Sullivan
Journal:  Brain Behav Immun       Date:  2020-07-31       Impact factor: 7.217

3.  Multiple Mild Traumatic Brain Injuries Are Associated with Increased Rates of Health Symptoms and Gulf War Illness in a Cohort of 1990-1991 Gulf War Veterans.

Authors:  Megan K Yee; Patricia A Janulewicz; Daniel R Seichepine; Kimberly A Sullivan; Susan P Proctor; Maxine H Krengel
Journal:  Brain Sci       Date:  2017-07-09

4.  The Multiple Hit Hypothesis for Gulf War Illness: Self-Reported Chemical/Biological Weapons Exposure and Mild Traumatic Brain Injury.

Authors:  Patricia Janulewicz; Maxine Krengel; Emily Quinn; Timothy Heeren; Rosemary Toomey; Ronald Killiany; Clara Zundel; Joy Ajama; James O'Callaghan; Lea Steele; Nancy Klimas; Kimberly Sullivan
Journal:  Brain Sci       Date:  2018-11-13

5.  Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness.

Authors:  Kristin F Phillips; Edna Santos; Robert E Blair; Laxmikant S Deshpande
Journal:  Toxicol Sci       Date:  2019-06-01       Impact factor: 4.849

Review 6.  Neuropsychological Findings in Gulf War Illness: A Review.

Authors:  Mary G Jeffrey; Maxine Krengel; Jeffrey L Kibler; Clara Zundel; Nancy G Klimas; Kimberly Sullivan; Travis J A Craddock
Journal:  Front Psychol       Date:  2019-09-26

7.  A randomized phase II remote study to assess Bacopa for Gulf War Illness associated cognitive dysfunction: Design and methods of a national study.

Authors:  Amanpreet K Cheema; Laura E Wiener; Rebecca B McNeil; Maria M Abreu; Travis Craddock; Mary A Fletcher; Drew A Helmer; J Wesson Ashford; Kimberly Sullivan; Nancy G Klimas
Journal:  Life Sci       Date:  2021-07-10       Impact factor: 6.780

8.  Changes in Health Status in the Ft. Devens Gulf War Veterans Cohort: 1997-2017.

Authors:  Clara G Zundel; Timothy Heeren; Claudia M Grasso; Avron Spiro; Susan P Proctor; Kimberly Sullivan; Maxine Krengel
Journal:  Neurosci Insights       Date:  2020-08-20

9.  The Prevalence of Mild Cognitive Impairment in a Convenience Sample of 202 Gulf War Veterans.

Authors:  Linda L Chao
Journal:  Int J Environ Res Public Health       Date:  2020-09-30       Impact factor: 3.390

10.  Longitudinal Assessment of Health Symptoms in Relation to Neurotoxicant Exposures in 1991 Gulf War Veterans: The Ft. Devens Cohort.

Authors:  Megan K Yee; Clara G Zundel; Alexis L Maule; Timothy Heeren; Susan P Proctor; Kimberly A Sullivan; Maxine H Krengel
Journal:  J Occup Environ Med       Date:  2020-09       Impact factor: 2.306

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