Literature DB >> 26291513

There Are Sex Differences in the Demographics and Risk Profiles of Emergency Department (ED) Patients With Atrial Fibrillation and Flutter, but no Apparent Differences in ED Management or Outcomes.

Frank Xavier Scheuermeyer1, Martha Mackay2, Jim Christenson1, Eric Grafstein3, Reza Pourvali1, Claire Heslop1, Jan MacPhee1, John Ward1, Brett Heilbron2, Lorraine McGrath2, Karin Humphries2.   

Abstract

OBJECTIVES: In non-emergency department (ED) settings, women with atrial fibrillation and flutter (AFF) have different presentations, treatments, and outcomes than men: they are older, less likely to be treated with rhythm control strategies or appropriate anticoagulation, and more likely to have strokes. This has not been investigated in ED patients.
METHODS: Records from consecutive ED patients from January 1 to December 31, 2009, with electrocardiogram-proven AFF at two urban hospitals were collected. Review of administrative and clinical data identified patient demographics, clinical characteristics, comorbidities, and ED treatments. The regional ED database was queried to determine 30-day and 1-year follow-up visits, and the provincial vital statistics database was referenced to obtain 30-day and 1-year mortality; all outcomes were stratified by sex. The primary outcome, which reflected overall appropriateness of ED care, was the proportion of patients who were discharged home at their index ED visits, who then had unscheduled 30-day ED revisits. Secondary outcomes included the proportion of eligible patients who underwent acute rhythm control strategies and the proportion of high-risk patients who had previously inadequately anticoagulation strategies corrected by the emergency physician. Additional outcomes included the ED length of stay (LOS) and 30-day and 1-year rates of stroke and death.
RESULTS: A total of 1,112 records were reviewed: 470 women (42.3%) and 642 men. Women were a median 8 years (interquartile range = 3 to 13 years) older than men, had higher rates of cardiovascular comorbidities, and were more likely to present with atypical symptoms such as weakness or dyspnea. On their index ED visits, 50.2% of women and 41.3% of men were admitted. At 30 days, 39 of 234 (16.7%) women and 55 of 377 (14.6%) men who were discharged at their index ED visits had made revisits, for a risk difference of 2.1% (95% confidence interval = -3.9% to 8.5%). There were no apparent sex differences in the use of acute rhythm control or in the appropriateness of anticoagulation decisions. ED LOS was similar between women and men, as were 30-day and 1-year stroke or death rates.
CONCLUSIONS: Female ED AFF patients were older, had more comorbidities, and were more likely to be admitted. However, the overall management and outcomes, including 30-day revisits, appeared to be similar to that of males, indicating that there appeared to be little sex-based discrepancy in ED care and outcomes.
© 2015 by the Society for Academic Emergency Medicine.

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Year:  2015        PMID: 26291513     DOI: 10.1111/acem.12750

Source DB:  PubMed          Journal:  Acad Emerg Med        ISSN: 1069-6563            Impact factor:   3.451


  9 in total

Review 1.  Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis.

Authors:  Darae Ko; Faisal Rahman; Renate B Schnabel; Xiaoyan Yin; Emelia J Benjamin; Ingrid E Christophersen
Journal:  Nat Rev Cardiol       Date:  2016-04-07       Impact factor: 32.419

2.  Mortality in patients with atrial fibrillation and common co-morbidities - a cohort study in primary care.

Authors:  Per Wändell; Axel C Carlsson; Martin J Holzmann; Johan Ärnlöv; Jan Sundquist; Kristina Sundquist
Journal:  Ann Med       Date:  2017-11-27       Impact factor: 4.709

3.  Sex Differences in Epicardial Adipose Tissue: Association With Atrial Fibrillation Ablation Outcomes.

Authors:  Jing Zhu; Kaimin Zhuo; Bo Zhang; Zhen Xie; Wenjia Li
Journal:  Front Cardiovasc Med       Date:  2022-06-13

4.  Characteristics of Atrial Fibrillation Patients with a Family History of Atrial Fibrillation.

Authors:  Shannon M Fan; Amy Fann; Gregory Nah; Mark J Pletcher; Jeffrey E Olgin; Gregory M Marcus
Journal:  J Atr Fibrillation       Date:  2019-06-30

Review 5.  Women and atrial fibrillation.

Authors:  Annabelle Santos Volgman; Emelia J Benjamin; Anne B Curtis; Margaret C Fang; Kathryn J Lindley; Gerald V Naccarelli; Carl J Pepine; Odayme Quesada; Marmar Vaseghi; Albert L Waldo; Nanette K Wenger; Andrea M Russo
Journal:  J Cardiovasc Electrophysiol       Date:  2020-12-29       Impact factor: 2.942

6.  Sex differences in management and outcomes of patients with atrial fibrillation in the Middle East: Gulf survey of atrial fibrillation events (Gulf SAFE).

Authors:  Abdulla Shehab; Mohammad Zubaid; Akshaya Srikanth Bhagavathula; Wafa A Rashed; Alawi A Alsheikh-Ali; Wal AlMahmeed; Kadhim Sulaiman; Ibrahim Al-Zakwani; Ahmed AlQudaimi; Nidal Asaad; Haitham Amin
Journal:  PLoS One       Date:  2017-05-17       Impact factor: 3.240

7.  The prevalence of atrial fibrillation in Greenland: a register-based cross-sectional study based on disease classifications and prescriptions of oral anticoagulants.

Authors:  N Albertsen; S Riahi; M L Pedersen; N Skovgaard; S Andersen
Journal:  Int J Circumpolar Health       Date:  2022-12       Impact factor: 1.228

Review 8.  Current Understanding of Molecular Pathophysiology of Heart Failure With Preserved Ejection Fraction.

Authors:  Heidi Budde; Roua Hassoun; Andreas Mügge; Árpád Kovács; Nazha Hamdani
Journal:  Front Physiol       Date:  2022-07-07       Impact factor: 4.755

Review 9.  Psychological aspects of atrial fibrillation: A systematic narrative review : Impact on incidence, cognition, prognosis, and symptom perception.

Authors:  Karl-Heinz Ladwig; Andreas Goette; Seryan Atasoy; Hamimatunnisa Johar
Journal:  Curr Cardiol Rep       Date:  2020-09-10       Impact factor: 2.931

  9 in total

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