Literature DB >> 26287588

LRRK2 and Nod2 promote lysozyme sorting in Paneth cells.

Juliana D B Rocha1, Michael G Schlossmacher2, Dana J Philpott1.   

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Year:  2015        PMID: 26287588     DOI: 10.1038/ni.3255

Source DB:  PubMed          Journal:  Nat Immunol        ISSN: 1529-2908            Impact factor:   25.606


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  17 in total

1.  Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.

Authors:  T Ayabe; D P Satchell; C L Wilson; W C Parks; M E Selsted; A J Ouellette
Journal:  Nat Immunol       Date:  2000-08       Impact factor: 25.606

2.  Commensal bacteria direct selective cargo sorting to promote symbiosis.

Authors:  Qin Zhang; Ying Pan; Ruiqing Yan; Benhua Zeng; Haifang Wang; Xinwen Zhang; Wenxia Li; Hong Wei; Zhihua Liu
Journal:  Nat Immunol       Date:  2015-08-03       Impact factor: 25.606

3.  Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.

Authors:  Antony A Cooper; Aaron D Gitler; Anil Cashikar; Cole M Haynes; Kathryn J Hill; Bhupinder Bhullar; Kangning Liu; Kexiang Xu; Katherine E Strathearn; Fang Liu; Songsong Cao; Kim A Caldwell; Guy A Caldwell; Gerald Marsischky; Richard D Kolodner; Joshua Labaer; Jean-Christophe Rochet; Nancy M Bonini; Susan Lindquist
Journal:  Science       Date:  2006-06-22       Impact factor: 47.728

Review 4.  Paneth cells: maestros of the small intestinal crypts.

Authors:  Hans C Clevers; Charles L Bevins
Journal:  Annu Rev Physiol       Date:  2013       Impact factor: 19.318

5.  An early endosome regulator, Rab5b, is an LRRK2 kinase substrate.

Authors:  Hye Jin Yun; Hyejung Kim; Inhwa Ga; Hakjin Oh; Dong Hwan Ho; Jiyoung Kim; Hyemyung Seo; Ilhong Son; Wongi Seol
Journal:  J Biochem       Date:  2015-01-19       Impact factor: 3.387

6.  Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.

Authors:  Kara G Lassen; Petric Kuballa; Kara L Conway; Khushbu K Patel; Christine E Becker; Joanna M Peloquin; Eduardo J Villablanca; Jason M Norman; Ta-Chiang Liu; Robert J Heath; Morgan L Becker; Lola Fagbami; Heiko Horn; Johnathan Mercer; Omer H Yilmaz; Jacob D Jaffe; Alykhan F Shamji; Atul K Bhan; Steven A Carr; Mark J Daly; Herbert W Virgin; Stuart L Schreiber; Thaddeus S Stappenbeck; Ramnik J Xavier
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-12       Impact factor: 11.205

7.  Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

Authors:  Henner F Farin; Wouter R Karthaus; Pekka Kujala; Maryam Rakhshandehroo; Gerald Schwank; Robert G J Vries; Eric Kalkhoven; Edward E S Nieuwenhuis; Hans Clevers
Journal:  J Exp Med       Date:  2014-06-30       Impact factor: 14.307

8.  UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans.

Authors:  Marija Sumakovic; Jan Hegermann; Ling Luo; Steven J Husson; Katrin Schwarze; Christian Olendrowitz; Liliane Schoofs; Janet Richmond; Stefan Eimer
Journal:  J Cell Biol       Date:  2009-09-21       Impact factor: 10.539

Review 9.  Deciphering the function of leucine-rich repeat kinase 2 and targeting its dysfunction in disease.

Authors:  Patrick A Lewis; Dario R Alessi
Journal:  Biochem Soc Trans       Date:  2012-10       Impact factor: 5.407

10.  Paneth cells as a site of origin for intestinal inflammation.

Authors:  Timon E Adolph; Michal F Tomczak; Lukas Niederreiter; Hyun-Jeong Ko; Janne Böck; Eduardo Martinez-Naves; Jonathan N Glickman; Markus Tschurtschenthaler; John Hartwig; Shuhei Hosomi; Magdalena B Flak; Jennifer L Cusick; Kenji Kohno; Takao Iwawaki; Susanne Billmann-Born; Tim Raine; Richa Bharti; Ralph Lucius; Mi-Na Kweon; Stefan J Marciniak; Augustine Choi; Susan J Hagen; Stefan Schreiber; Philip Rosenstiel; Arthur Kaser; Richard S Blumberg
Journal:  Nature       Date:  2013-10-02       Impact factor: 49.962

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  11 in total

Review 1.  Links of Autophagy Dysfunction to Inflammatory Bowel Disease Onset.

Authors:  Faris El-Khider; Christine McDonald
Journal:  Dig Dis       Date:  2016-03-16       Impact factor: 2.404

2.  IL-1α and IL-1β promote NOD2-induced immune responses by enhancing MAPK signaling.

Authors:  Sushan Li; Ping Deng; Manzhi Wang; Xueting Liu; Manli Jiang; Binyuan Jiang; Li Yang; Jinyue Hu
Journal:  Lab Invest       Date:  2019-04-24       Impact factor: 5.662

Review 3.  Stem Cells in Repair of Gastrointestinal Epithelia.

Authors:  Amanda Andersson-Rolf; Matthias Zilbauer; Bon-Kyoung Koo; Hans Clevers
Journal:  Physiology (Bethesda)       Date:  2017-07

Review 4.  Intestinal Autophagy and Its Pharmacological Control in Inflammatory Bowel Disease.

Authors:  Ping Ke; Bo-Zong Shao; Zhe-Qi Xu; Xiong-Wen Chen; Chong Liu
Journal:  Front Immunol       Date:  2017-01-09       Impact factor: 7.561

5.  Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the PR EDIGT score.

Authors:  Michael G Schlossmacher; Julianna J Tomlinson; Goncalo Santos; Bojan Shutinoski; Earl G Brown; Douglas Manuel; Tiago Mestre
Journal:  Eur J Neurosci       Date:  2016-12-27       Impact factor: 3.386

Review 6.  Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease.

Authors:  Shu-Ling Wang; Bo-Zong Shao; Sheng-Bing Zhao; Jun Fang; Lun Gu; Chao-Yu Miao; Zhao-Shen Li; Yu Bai
Journal:  Front Immunol       Date:  2018-04-05       Impact factor: 7.561

7.  LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.

Authors:  Anetta Härtlova; Susanne Herbst; Julien Peltier; Angela Rodgers; Orsolya Bilkei-Gorzo; Antony Fearns; Brian D Dill; Heyne Lee; Rowan Flynn; Sally A Cowley; Paul Davies; Patrick A Lewis; Ian G Ganley; Jennifer Martinez; Dario R Alessi; Alastair D Reith; Matthias Trost; Maximiliano G Gutierrez
Journal:  EMBO J       Date:  2018-05-22       Impact factor: 14.012

Review 8.  Intestinal enteroids/organoids: A novel platform for drug discovery in inflammatory bowel diseases.

Authors:  Jun-Hwan Yoo; Mark Donowitz
Journal:  World J Gastroenterol       Date:  2019-08-14       Impact factor: 5.374

9.  HPS1 Regulates the Maturation of Large Dense Core Vesicles and Lysozyme Secretion in Paneth Cells.

Authors:  Jiaying Yu; Xin He; Aihua Wei; Teng Liu; Qin Zhang; Ying Pan; Zhenhua Hao; Lin Yang; Yefeng Yuan; Zhao Zhang; Chang Zhang; Chanjuan Hao; Zhihua Liu; Wei Li
Journal:  Front Immunol       Date:  2020-11-05       Impact factor: 7.561

Review 10.  NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated Carcinogenesis.

Authors:  Audrey Ferrand; Ziad Al Nabhani; Núria Solà Tapias; Emmanuel Mas; Jean-Pierre Hugot; Frédérick Barreau
Journal:  Cell Mol Gastroenterol Hepatol       Date:  2018-10-23
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