Wenzhi Li1, Guoxing Fu2, Weinian Rao2, Wei Xu3, Li Ma4, Shiwen Guo5, Qing Song6. 1. Department of Neurosurgery, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China, Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA. 2. 4DGENOME Inc, Atlanta, GA, 30033 USA and. 3. Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA. 4. Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA, 4DGENOME Inc, Atlanta, GA, 30033 USA and. 5. Department of Neurosurgery, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China. 6. Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA, 4DGENOME Inc, Atlanta, GA, 30033 USA and Center of Big Data and Bioinformatics, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China.
Abstract
UNLABELLED: We present a software tool called GenomeLaser that determines the haplotypes of each person from unphased high-throughput genotypes in family pedigrees. This method features high accuracy, chromosome-range phasing distance, linear computing, flexible pedigree types and flexible genetic marker types. AVAILABILITY AND IMPLEMENTATION: http://www.4dgenome.com/software/genomelaser.html.
UNLABELLED: We present a software tool called GenomeLaser that determines the haplotypes of each person from unphased high-throughput genotypes in family pedigrees. This method features high accuracy, chromosome-range phasing distance, linear computing, flexible pedigree types and flexible genetic marker types. AVAILABILITY AND IMPLEMENTATION: http://www.4dgenome.com/software/genomelaser.html.
Authors: Ewen F Kirkness; Rashel V Grindberg; Joyclyn Yee-Greenbaum; Christian R Marshall; Stephen W Scherer; Roger S Lasken; J Craig Venter Journal: Genome Res Date: 2013-01-02 Impact factor: 9.043