| Literature DB >> 26284490 |
Kurt Fuursted1, Lillian Marie Søes2, Bjørn Thomas Crewe3, Marc Stegger4, Paal Skytt Andersen4, Jens Jørgen Christensen2.
Abstract
A non-toxigenic tox gene-bearing (NTTB) Corynebacterium ulcerans was grown from the wound of a 61-year-old gardener and in a nasal specimen from the patient's asymptomatic dog. The two isolates were similar in terms of antibiogram, multilocus sequence typing (ST341), virulence genes, and only three SNPs were found to differentiate the two NTTB C. ulcerans isolates supporting a zoonotic transmission to or between the patient and his dog. Of interest, we found that the two C. ulcerans isolates, although not expressing the diphtheria toxin tox, possessed 13 out of 14 recently described virulence candidate genes.Entities:
Keywords: Dog; Next generation sequencing; Non-toxigenic but tox gene bearing (NTTB) Corynebacterium ulcerans; Whole-genome sequencing; Wound infection
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Year: 2015 PMID： 26284490 DOI： 10.1016/j.micinf.2015.07.004
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700