Literature DB >> 26283825

Effects of fluconazole, chlorhexidine gluconate, and silver-zinc zeolite on flexural strength of heat-cured polymethyl methacrylate resin.

Naveen S Yadav1, Sneha Saraf1, Sunil Kumar Mishra1, Puja Hazari1.   

Abstract

AIM: We evaluated the effect of incorporating Fluconazole, Chlorhexidine Gluconate, and Silver-Zinc Zeolite as bioactive materials (10% of mass) on the flexural strength of commercially available heat-cured polymethyl methacrylate (PMMA; Travelon).
MATERIALS AND METHODS: The following four groups were compared; Group 1: Control group with pure PMMA, Group 2: Antibacterial drug group with chlorhexidine gluconate in powder form + PMMA, Group 3: Antifungal drug group with fluconazole in powder form + PMMA, Group 4: Antimicrobial agent group with silver zinc zeolite in powder form + PMMA. After processing, the specimens were subjected for flexural strength testing using three-point bending test in a universal testing machine.
RESULTS: A significant (P < 0.0001) decrease in flexural strength following incorporation of Fluconazole, Chlorhexidine Gluconate, and Silver-Zinc Zeolite to heat polymerized acrylic resin was observed when compared with the control group. The decrease in mean flexural strength was minimal in the fluconazole group.
CONCLUSION: Although the addition of a bioactive material to PMMA acrylic is desirable, it is not practical as it reduces flexural strength of the acrylic base.

Entities:  

Keywords:  Bioactive compounds; chlorhexidine gluconate; flexural strength; fluconazole; polymethyl methacrylate; silver-zinc zeolite

Year:  2015        PMID: 26283825      PMCID: PMC4518405          DOI: 10.4103/0976-9668.159999

Source DB:  PubMed          Journal:  J Nat Sci Biol Med        ISSN: 0976-9668


  16 in total

1.  The effect of disinfection procedures on flexural properties of denture base acrylic resins.

Authors:  T Asad; A C Watkinson; R Huggett
Journal:  J Prosthet Dent       Date:  1992-07       Impact factor: 3.426

2.  Flexural properties of glass fibre reinforced acrylic resin polymers.

Authors:  I H Tacir; J D Kama; M Zortuk; S Eskimez
Journal:  Aust Dent J       Date:  2006-03       Impact factor: 2.291

3.  Assessment of flexural strength and color alteration of heat-polymerized acrylic resins after simulated use of denture cleansers.

Authors:  Sandra Sato; Márcia Rosa Sobreira Cavalcante; Iara Augusta Orsi; Helena de Freitas Oliveira Paranhos; Osvaldo Zaniquelli
Journal:  Braz Dent J       Date:  2005

4.  Antifungal effect of zeolite-incorporated tissue conditioner against Candida albicans growth and/or acid production.

Authors:  H Nikawa; T Yamamoto; T Hamada; M B Rahardjo; H Murata; S Nakanoda
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Journal:  Oral Dis       Date:  1996-12       Impact factor: 3.511

6.  The effect of variations in the polymer/monomer mixing ratios on residual monomer levels and flexural properties of denture base materials.

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Journal:  Quintessence Dent Technol       Date:  1985 Jul-Aug

7.  Antimicrobial and mechanical properties of acrylic resins with incorporated silver-zinc zeolite - part I.

Authors:  Luciana Assirati Casemiro; Carlos Henrique Gomes Martins; Fernanda de Carvalho Panzeri Pires-de-Souza; Heitor Panzeri
Journal:  Gerodontology       Date:  2008-01-13       Impact factor: 2.980

8.  The effects of the incorporation of chlorhexidine acetate on some physical properties of polymerized and plasticized acrylics.

Authors:  M Addy; R Handley
Journal:  J Oral Rehabil       Date:  1981-03       Impact factor: 3.837

9.  A Comparison of the eFficacy of Nystatin and Fluconazole Incorporated into Tissue Conditioner on the In Vitro Attachment and Colonization of Candida Albicans.

Authors:  Abbas Falah-Tafti; Abbas Ali Jafari; Mohammad Hossein Lotfi-Kamran; Hossein Fallahzadeh; Reyhana Sadat Hayan
Journal:  Dent Res J (Isfahan)       Date:  2010

10.  A new form of intraoral delivery of antifungal drugs for the treatment of denture-induced oral candidosis.

Authors:  Wala M Amin; Muna H Al-Ali; Nesreen A Salim; Sandra K Al-Tarawneh
Journal:  Eur J Dent       Date:  2009-10
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  1 in total

Review 1.  Antimicrobial and Mechanical Effects of Zeolite Use in Dental Materials: A Systematic Review.

Authors:  Jessica Hao; Spencer Lang; Francis Mante; Kresimir Pavelić; Fusun Ozer
Journal:  Acta Stomatol Croat       Date:  2021-03
  1 in total

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