J A Farras Roca1, T H Dao1, L Lantieri2, C Lepage2, R Bosc3, E Meyblum1, F Pigneur1, P Beaussart1, E Assaf4, J L Totobenazara5, E Calitchi6, Y Belkacemi7, A Rahmouni8, A Luciani9. 1. Service d'imagerie médicale, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. 2. Service de chirurgie plastique et reconstructrice, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75015 Paris, France. 3. Service de chirurgie plastique et reconstructrice, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. 4. Service d'oncologie médicale, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. 5. Service d'anatomo-pathologie, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. 6. Service de radiothérapie, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. 7. Service de radiothérapie, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France; Faculté de médecine, université Paris Est, Créteil, France. 8. Service d'imagerie médicale, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France; Faculté de médecine, université Paris Est, Créteil, France. 9. Service d'imagerie médicale, groupe Henri-Mondor-Albert-Chenevier, centre sein Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France; Faculté de médecine, université Paris Est, Créteil, France. Electronic address: alain.luciani@hmn.aphp.fr.
Abstract
PURPOSE: To assess the incidence and presentation of ipsilateral cancer recurrences (ICR) after deep inferior epigastric perforator (DIEP) flap reconstruction for breast cancer. PATIENTS AND METHODS: Data of 247 consecutive women with DIEP flap reconstruction after breast cancer in our institution between 1997 and 2009 were retrospectively reviewed. RESULTS: Mean follow-up time was 4.1years±3.2 (SD) (median: 3years; range: 1month - 14years). Thirty-one patients (12.5%, 95%CI: =8.7-17.3) presented 34 relapses, in average 4.1years±2.6 after mastectomy: 14 (41%) were ipsilateral, 6 (18%) contralateral and 14 (41%) metastatic. ICRs occurred earlier (3.9 vs. 5.8years; P<0.05) than non-ICRs. Most ICRs (10/14, 71%) involved the periphery of the flap and presented as palpable nodules. The remaining (4/14, 29%) involved the axilla and 3/4 (75%) were palpable. Imaging procedures detected infra-clinical ICRs in 3 of 10 imaged patients (30%). CONCLUSION: ICRs after DIEP flap reconstruction are more frequent than contralateral recurrences suggesting the need for imaging follow-up of the reconstructed breast.
PURPOSE: To assess the incidence and presentation of ipsilateral cancer recurrences (ICR) after deep inferior epigastric perforator (DIEP) flap reconstruction for breast cancer. PATIENTS AND METHODS: Data of 247 consecutive women with DIEP flap reconstruction after breast cancer in our institution between 1997 and 2009 were retrospectively reviewed. RESULTS: Mean follow-up time was 4.1years±3.2 (SD) (median: 3years; range: 1month - 14years). Thirty-one patients (12.5%, 95%CI: =8.7-17.3) presented 34 relapses, in average 4.1years±2.6 after mastectomy: 14 (41%) were ipsilateral, 6 (18%) contralateral and 14 (41%) metastatic. ICRs occurred earlier (3.9 vs. 5.8years; P<0.05) than non-ICRs. Most ICRs (10/14, 71%) involved the periphery of the flap and presented as palpable nodules. The remaining (4/14, 29%) involved the axilla and 3/4 (75%) were palpable. Imaging procedures detected infra-clinical ICRs in 3 of 10 imaged patients (30%). CONCLUSION: ICRs after DIEP flap reconstruction are more frequent than contralateral recurrences suggesting the need for imaging follow-up of the reconstructed breast.
Authors: Elizabeth A Brett; Matthias M Aitzetmüller; Matthias A Sauter; Georg M Huemer; Hans-Günther Machens; Dominik Duscher Journal: Oncotarget Date: 2018-06-12
Authors: Nicholas Lao; Muriel Brackstone; Silvia C Formenti; Christopher Doherty; Francisco Perera; Ronald Chow; Tanya DeLyzer; Aaron Grant; Gabriel Boldt; Michael Lock Journal: Clin Transl Radiat Oncol Date: 2021-05-06