Literature DB >> 26279736

Malignant epitheloid angiomyolipoma of the kidney in a child treated with sunitinib, everolimus and axitinib.

Elvan Caglar Citak1, Eda Bengi Yilmaz2, Emel Yaman3, Simge Kaya1, Hakan Taskinlar4, Rabia Bozdogan Arpaci5, Demir Apaydin6.   

Abstract

The malignant variant of epithelioid angiomyolipoma (EAML) of the kidney is uncommon, extremely aggressive and behaves like a renal cell carcinoma. We present a case of a 12-year-old male with malignant EAML who was treated according to adult treatment protocols. To our knowledge, axitinib has not been used before in children. We conclude that adult protocols, in this rare case, could be safely used in rare childhood malignancies.

Entities:  

Year:  2015        PMID： 26279736      PMCID： PMC4514512          DOI： 10.5489/cuaj.2823

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN： 1911-6470            Impact factor:   1.862


  4 in total

Review 1.  Pure epitheliod perivascular epitheloid cell tumor (epitheliod angiomyolipoma) of kidney: case report and literature review.

Authors:  P G Jayaprakash; Susan Mathews; M Biju Azariah; Geethu Babu
Journal:  J Cancer Res Ther       Date:  2014 Apr-Jun       Impact factor: 1.805

2.  Multicenter phase II study of sunitinib in patients with non-clear cell renal cell carcinoma.

Authors:  J-L Lee; J-H Ahn; H Y Lim; S H Park; S H Lee; T M Kim; D-H Lee; Y M Cho; C Song; J H Hong; C-S Kim; H Ahn
Journal:  Ann Oncol       Date:  2012-01-06       Impact factor: 32.976

3.  Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial.

Authors:  John J Bissler; J Christopher Kingswood; Elżbieta Radzikowska; Bernard A Zonnenberg; Michael Frost; Elena Belousova; Matthias Sauter; Norio Nonomura; Susanne Brakemeier; Petrus J de Vries; Vicky H Whittemore; David Chen; Tarek Sahmoud; Gaurav Shah; Jeremie Lincy; David Lebwohl; Klemens Budde
Journal:  Lancet       Date:  2013-03-09       Impact factor: 79.321

4.  Fatal malignant metastastic epithelioid angiomyolipoma presenting in a young woman: case report and review of the literature.

Authors:  Edward Wyluda; Giselle Baquero; Nicholas Lamparella; Catherine Abendroth; Joseph Drabick
Journal:  Rare Tumors       Date:  2013-09-26
  4 in total
  6 in total

1.  Evaluation of renal tumors in children.

Authors:  Gülçin Bozlu; Elvan Çağlar Çıtak
Journal:  Turk J Urol       Date:  2018-05-01

2.  Metastatic epithelioid angiomyolipoma treated with everolimus in a patient receiving hemodialysis: A case report.

Authors:  Manabu Takai; Koji Kameyama; Shohei Toyota; Shingo Kamei; Shigeaki Yokoi; Satoshi Ishihara; Takashi Deguchi
Journal:  IJU Case Rep       Date:  2019-07-09

3.  Combination of Everolimus with Sorafenib for Solid Renal Tumors in Tsc2+/- Mice Is Superior to Everolimus Alone.

Authors:  Jian Yang; Paulina A Samsel; Kalin Narov; Ashley Jones; Daniel Gallacher; John Gallacher; Julian R Sampson; Ming Hong Shen
Journal:  Neoplasia       Date:  2017-01-13       Impact factor: 5.715

4.  Everolimus in Invasive Malignant Renal Epithelioid Angiomyolipoma.

Authors:  Gang Guo; Liangyou Gu; Xu Zhang
Journal:  Front Oncol       Date:  2021-01-26       Impact factor: 6.244

5.  Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.

Authors:  Marta Espinosa; Juan Maria Roldán-Romero; Ignacio Duran; Enrique de Álava; María Apellaniz-Ruiz; Alberto Cascón; Carmen Garrigos; Mercedes Robledo; Cristina Rodriguez-Antona
Journal:  BMC Cancer       Date:  2018-05-15       Impact factor: 4.430

6.  Renal Epithelioid Angiomyolipoma in Children.

Authors:  Dhruv Mahajan; Vishesh Jain; Sandeep Agarwala; Manisha Jana; Prashant P Ramteke
Journal:  J Kidney Cancer VHL       Date:  2021-06-04
  6 in total

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