OBJECTIVE: To evaluate the intermediate intracardiac diastolic velocities in fetuses with growth restriction. METHODS: Doppler waveforms of the two atrioventricular valves were obtained. Peak velocities of the E (early) and A (atrial) components, and the lowest intermediate velocity (IDV) between them, were measured in 400 normally grown and in 100 growth-restricted fetuses. The prevalence of abnormal IDV, E/IDV, and A/IDV ratios in fetuses presenting with perinatal death or acidemia at birth (pH ≤7.1) was estimated. RESULTS: IDV was significantly lower and E/IDV ratios significantly higher in the two ventricles of growth-restricted fetuses with reduced diastolic velocities in the umbilical artery (p < 0.05). In 13 fetuses presenting with perinatal death or acidemia at birth, 11 (85%) had either an E/IDV or A/IDV ratio >95th percentile, whereas 5 (38%) showed absent or reversed atrial velocities in the ductus venosus (DV-ARAV; p < 0.04). Fetuses without DV-ARAV but with elevated E/IDV ratios in either ventricle were nearly 7-fold more likely to have perinatal demise or acidemia at birth (OR 6.9, 95% CI 1.4-34) than those with E/IDV ratios <95th percentile. CONCLUSION: The E/IDV and A/IDV ratios in the two cardiac ventricles might provide information about the risk of perinatal demise or acidemia in growth-restricted fetuses.
OBJECTIVE: To evaluate the intermediate intracardiac diastolic velocities in fetuses with growth restriction. METHODS: Doppler waveforms of the two atrioventricular valves were obtained. Peak velocities of the E (early) and A (atrial) components, and the lowest intermediate velocity (IDV) between them, were measured in 400 normally grown and in 100 growth-restricted fetuses. The prevalence of abnormal IDV, E/IDV, and A/IDV ratios in fetuses presenting with perinatal death or acidemia at birth (pH ≤7.1) was estimated. RESULTS: IDV was significantly lower and E/IDV ratios significantly higher in the two ventricles of growth-restricted fetuses with reduced diastolic velocities in the umbilical artery (p < 0.05). In 13 fetuses presenting with perinatal death or acidemia at birth, 11 (85%) had either an E/IDV or A/IDV ratio >95th percentile, whereas 5 (38%) showed absent or reversed atrial velocities in the ductus venosus (DV-ARAV; p < 0.04). Fetuses without DV-ARAV but with elevated E/IDV ratios in either ventricle were nearly 7-fold more likely to have perinatal demise or acidemia at birth (OR 6.9, 95% CI 1.4-34) than those with E/IDV ratios <95th percentile. CONCLUSION: The E/IDV and A/IDV ratios in the two cardiac ventricles might provide information about the risk of perinatal demise or acidemia in growth-restricted fetuses.
Authors: R Romero; J Espinoza; L F Gonçalves; R Gomez; L Medina; M Silva; T Chaiworapongsa; B H Yoon; F Ghezzi; W Lee; M Treadwell; S M Berry; E Maymon; M Mazor; G DeVore Journal: J Matern Fetal Neonatal Med Date: 2004-09
Authors: M Cruz-Lemini; F Crispi; B Valenzuela-Alcaraz; F Figueras; M Sitges; O Gómez; B Bijnens; E Gratacós Journal: Ultrasound Obstet Gynecol Date: 2013-06-24 Impact factor: 7.299
Authors: Rodney Paiva Vasconcelos; José Richelmy Brazil Frota Aragão; Francisco Herlânio Costa Carvalho; Rosa Maria Salani Mota; Francisco Edson de Lucena Feitosa; Carlos Augusto Alencar Júnior Journal: Fetal Diagn Ther Date: 2010-09-16 Impact factor: 2.587