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Literature DB >> 26277434

A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique.

Jian-Yue Jin¹, Bo Zhao², Joseph M Kaminski³, Ning Wen², Yimei Huang², John Vender⁴, Indrin J Chetty², Feng-Ming Spring Kong³.

Abstract

This study presents a MLC-based, 3D grid-therapy technique with characteristics of both 3D-conformal-radiotherapy and grid-therapy. It generates a brachytherapy-like dose distribution, with D50% of 20, 9.8, 5.4 and 2.9-Gy, for the spheres, target, 1 cm-outershell and 2 cm-outershell, respectively. It may provide a strategy to deliver ablative doses to large tumors safely.

Entities: Disease Gene

Keywords: Ablative radiation; Film dosimetry; Grid therapy; Immune-response; Spatially fractionated radiotherapy

Mesh：

Year: 2015 PMID： 26277434 DOI： 10.1016/j.radonc.2015.07.047

Source DB: PubMed Journal: Radiother Oncol ISSN： 0167-8140 Impact factor: 6.280

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Cited

5 in total

1. A novel, yet simple MLC-based 3D-crossfire technique for spatially fractionated GRID therapy treatment of deep-seated bulky tumors.

Authors: Damodar Pokhrel; Matthew Halfman; Lana Sanford; Quan Chen; Mahesh Kudrimoti
Journal: J Appl Clin Med Phys Date: 2020-02-08 Impact factor: 2.102

5. A simple dosimetric approach to spatially fractionated GRID radiation therapy using the multileaf collimator for treatment of breast cancers in the prone position.

Authors: Natasha L Murphy; Rino Philip; Matt Wozniak; Brian H Lee; Eric D Donnelly; Hualin Zhang
Journal: J Appl Clin Med Phys Date: 2020-10-29 Impact factor: 2.243

5 in total

A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique.

1. A novel, yet simple MLC-based 3D-crossfire technique for spatially fractionated GRID therapy treatment of deep-seated bulky tumors.

2. Conebeam CT-guided 3D MLC-based spatially fractionated radiation therapy for bulky masses.

3. Is grid therapy useful for all tumors and every grid block design?

Review 4. Radiobiological and Treatment-Related Aspects of Spatially Fractionated Radiotherapy.

5. A simple dosimetric approach to spatially fractionated GRID radiation therapy using the multileaf collimator for treatment of breast cancers in the prone position.