Literature DB >> 26276713

Tumor microenvironment: Sanctuary of the devil.

Lanlan Hui1, Ye Chen2.   

Abstract

Tumor cells constantly interact with the surrounding microenvironment. Increasing evidence indicates that targeting the tumor microenvironment could complement traditional treatment and improve therapeutic outcomes for these malignancies. In this paper, we review new insights into the tumor microenvironment, and summarize selected examples of the cross-talk between tumor cells and their microenvironment, which have enhanced our understanding of pathophysiology of the microenvironment. We believe that this rapidly moving field promises many more to come, and they will guide the rational design of combinational therapies for success in cancer eradication.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Combination therapy; Drug resistance; Tumor microenvironment

Mesh：

Year:  2015        PMID： 26276713     DOI： 10.1016/j.canlet.2015.07.039

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  249 in total

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Review 3.  Intratumoral Heterogeneity in Ductal Carcinoma In Situ: Chaos and Consequence.

Authors:  Vidya C Sinha; Helen Piwnica-Worms
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Review 4.  Emerging cellular functions of the lipid metabolizing enzyme 15-Lipoxygenase-1.

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Journal:  Cell Prolif       Date:  2018-07-30       Impact factor: 6.831

5.  Quantitative High-Throughput Screening Using an Organotypic Model Identifies Compounds that Inhibit Ovarian Cancer Metastasis.

Authors:  Hilary A Kenny; Madhu Lal-Nag; Min Shen; Betul Kara; Dominik A Nahotko; Kristen Wroblewski; Sarah Fazal; Siquan Chen; Chun-Yi Chiang; Yen-Ju Chen; Kyle R Brimacombe; Juan Marugan; Marc Ferrer; Ernst Lengyel
Journal:  Mol Cancer Ther       Date:  2019-09-27       Impact factor: 6.261

6.  CTLA4 has a profound impact on the landscape of tumor-infiltrating lymphocytes with a high prognosis value in clear cell renal cell carcinoma (ccRCC).

Authors:  Shiyi Liu; Feiyan Wang; Wei Tan; Li Zhang; Fangfang Dai; Yanqing Wang; Yaqi Fan; Mengqin Yuan; Dongyong Yang; Yajing Zheng; Zhimin Deng; Yeqiang Liu; Yanxiang Cheng
Journal:  Cancer Cell Int       Date:  2020-10-27       Impact factor: 5.722

Review 7.  Connections between metabolism and epigenetics in cancers.

Authors:  Chitra Thakur; Fei Chen
Journal:  Semin Cancer Biol       Date:  2019-06-08       Impact factor: 15.707

8.  Mitochondrial protective effect of neferine through the modulation of nuclear factor erythroid 2-related factor 2 signalling in ischaemic stroke.

Authors:  Chuanhong Wu; Jianxin Chen; Ruocong Yang; Feipeng Duan; Shaojing Li; Xiuping Chen
Journal:  Br J Pharmacol       Date:  2018-12-18       Impact factor: 8.739

9.  Macrophage-derived CCL18 promotes osteosarcoma proliferation and migration by upregulating the expression of UCA1.

Authors:  Yang Su; Yan Zhou; Yuan-Jue Sun; Ya-Ling Wang; Jun-Yi Yin; Yu-Jing Huang; Jian-Jun Zhang; Ai-Na He; Kun Han; Hui-Zhen Zhang; Yang Yao; Xiao-Bin Lv; Hai-Yan Hu
Journal:  J Mol Med (Berl)       Date:  2018-11-13       Impact factor: 4.599

Review 10.  Sweat Gland Tumor Microenvironment.

Authors:  Adeodatus Yuda Handaya; Sumadi Lukman Anwar; Aditya Rifqi Fauzi; Victor Agastya Pramudya Werdana
Journal:  Adv Exp Med Biol       Date:  2020       Impact factor: 2.622
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