| Literature DB >> 26276626 |
Zhe Liu1.
Abstract
In this issue, Shachar et al. report a high-throughput imaging position mapping platform (HIPmap) enabling large-scale, high-resolution localization of 3D gene positions in single cells. Coupling loss-of-function screens with HIPmap, the authors identify DNA replication rather than mitosis as a major determinant of genome positioning.Mesh:
Year: 2015 PMID: 26276626 DOI: 10.1016/j.cell.2015.07.052
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582