Literature DB >> 26276226

TET proteins in cancer: Current 'state of the art'.

Agnieszka Anna Rawłuszko-Wieczorek1, Agnieszka Siera2, Paweł Piotr Jagodziński2.   

Abstract

Aberrations in DNA methylation patterns are observed from the early stages of carcinogenesis. However, the mechanisms that drive these changes remain elusive. The recent characterization of ten-eleven translocation (TET) enzymes as a source of newly modified cytosines (5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine) has shed new light on the DNA demethylation process. These cytosines are intermediates of an active DNA demethylation process and are epigenetic markers per se. In this review, we discuss the mechanism and function of TET proteins in biological processes as well as current knowledge regarding their expression and regulation in cancer.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  5-hmC; Cancer; DNA methylation; TET

Mesh：

Substances：

Year:  2015        PMID： 26276226     DOI： 10.1016/j.critrevonc.2015.07.008

Source DB:  PubMed          Journal:  Crit Rev Oncol Hematol        ISSN： 1040-8428            Impact factor:   6.312


  9 in total

1.  Transcript levels of ten-eleven translocation type 1-3 in cervical cancer and non-cancerous cervical tissues.

Authors:  Dorota Ewa Bronowicka-Kłys; Andrzej Roszak; Piotr Pawlik; Stefan Sajdak; Anna Sowińska; Paweł Piotr Jagodziński
Journal:  Oncol Lett       Date:  2017-03-28       Impact factor: 2.967

Review 2.  Lymphoid-specific helicase in epigenetics, DNA repair and cancer.

Authors:  Xiangyu Chen; Yamei Li; Karla Rubio; Bi Deng; Yuyi Li; Qinwei Tang; Chao Mao; Shuang Liu; Desheng Xiao; Guillermo Barreto; Yongguang Tao
Journal:  Br J Cancer       Date:  2021-09-07       Impact factor: 9.075

3.  Drosophila Tet Is Required for Maintaining Glial Homeostasis in Developing and Adult Fly Brains.

Authors:  Felice Frey; Jawdat Sandakly; Mirna Ghannam; Caren Doueiry; Fredrik Hugosson; Johannes Berlandi; Joy N Ismail; Tenzin Gayden; Martin Hasselblatt; Nada Jabado; Margret Shirinian
Journal:  eNeuro       Date:  2022-04-26

Review 4.  Multiple Functions of Ten-eleven Translocation 1 during Tumorigenesis.

Authors:  Yi-Ping Tian; Yi-Min Zhu; Xiao-Hui Sun; Mao-De Lai
Journal:  Chin Med J (Engl)       Date:  2016-07-20       Impact factor: 2.628

5.  3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation.

Authors:  Xiaoli Peng; Hui Chang; Junli Chen; Qianyong Zhang; Xiaoping Yu; Mantian Mi
Journal:  BMC Cancer       Date:  2017-09-05       Impact factor: 4.430

6.  Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma.

Authors:  Fengkai Xu; Zhonghe Liu; Ronghua Liu; Chunlai Lu; Lin Wang; Wei Mao; Qiaoliang Zhu; Huankai Shou; Kunpeng Zhang; Yin Li; Yiwei Chu; Jie Gu; Di Ge
Journal:  Cell Commun Signal       Date:  2020-02-03       Impact factor: 5.712

Review 7.  Physical Activity and DNA Methylation in Humans.

Authors:  Witold Józef Światowy; Hanna Drzewiecka; Michalina Kliber; Maria Sąsiadek; Paweł Karpiński; Andrzej Pławski; Paweł Piotr Jagodziński
Journal:  Int J Mol Sci       Date:  2021-11-30       Impact factor: 5.923

8.  Loss of ten-eleven translocation 1 (TET1) expression as a diagnostic and prognostic biomarker of endometrial carcinoma.

Authors:  Nien-Tzu Liu; Cherng-Lih Perng; Yu-Ching Chou; Pi-Shao Ko; Yi-Jia Lin; Yu-Chun Lin; Cheng-Chang Chang; Yu-Chi Wang; Hung-Sheng Shang; Tai-Kuang Chao
Journal:  PLoS One       Date:  2021-11-03       Impact factor: 3.240

9.  Meta-Analysis of EMT Datasets Reveals Different Types of EMT.

Authors:  Lining Liang; Hao Sun; Wei Zhang; Mengdan Zhang; Xiao Yang; Rui Kuang; Hui Zheng
Journal:  PLoS One       Date:  2016-06-03       Impact factor: 3.240
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.