Literature DB >> 26275771

The relationship between craniofacial development and hypodontia in patients with Down syndrome.

D J F van Marrewijk1, M A E van Stiphout2, W Reuland-Bosma2, E M Bronkhorst3, E M Ongkosuwito4.   

Abstract

BACKGROUND/
OBJECTIVE: Hypodontia is often seen in people with Down syndrome (DS). In the normal population, persons with hypodontia have a shorter cranial base and a hypoplastic maxilla, leading to a skeletal Class III tendency and a reduced face height. The purpose of this study was to examine craniofacial morphology in patients with DS at different ages and the influence of hypodontia on their craniofacial morphology.
MATERIALS AND METHODS: A comparative cross-sectional study was conducted in 63 children with DS (6-19 years old; 28 males and 35 females) at a Centre for Special Care Dentistry in Rotterdam, the Netherlands (CBT Rijnmond). Digital lateral cephalograms were obtained from all subjects and a cephalometric analysis was performed. The subjects were divided into a group with hypodontia (13 males and 25 females) and a group without hypodontia (15 males and 10 females).
RESULTS: Significant results included a decrease in antero-posterior relationship of upper and lower jaw (ANB angle -0.331° per year, P = 0.044) and a decrease in vertical dimension (S-N_Go-Gn angle -0.72° per year, P = 0.039) over the years in subjects with hypodontia compared to subjects without hypodontia.
CONCLUSION: The process of growth in DS patients is towards a reversed overjet. Hypodontia seems to have an additional effect on this development. The management of hypodontia as part of the complete treatment of dental development in DS children is important because it strongly influences the jaw relationship.
© The Author 2015. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Entities:  

Mesh:

Year:  2015        PMID: 26275771      PMCID: PMC4914765          DOI: 10.1093/ejo/cjv054

Source DB:  PubMed          Journal:  Eur J Orthod        ISSN: 0141-5387            Impact factor:   3.075


  32 in total

1.  A quantitative study of the face in Down's syndrome.

Authors:  G B Fink; W K Madaus; G F Walker
Journal:  Am J Orthod       Date:  1975-05

Review 2.  Genetic mechanisms involved in the phenotype of Down syndrome.

Authors:  David Patterson
Journal:  Ment Retard Dev Disabil Res Rev       Date:  2007

3.  Hypodontia in patients with Down's syndrome.

Authors:  S R Mestrović; Z Rajić; J S Papić
Journal:  Coll Antropol       Date:  1998-12

Review 4.  Down syndrome: a review of the literature.

Authors:  S S Desai
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  1997-09

Review 5.  Skeletal alterations in Down's syndrome: bibliographic review and case study contribution.

Authors:  B De Luca; R Massimino; S Materazzo; V Lombardo; M Majorana
Journal:  Rays       Date:  1988 Sep-Dec

6.  Cephalometric comparison between children with and without Down's syndrome.

Authors:  H Fischer-Brandies
Journal:  Eur J Orthod       Date:  1988-08       Impact factor: 3.075

7.  Dental considerations for individuals with Down syndrome.

Authors:  Patricia Seagriff-Curtin; Susan Pugliese; Maureen Romer
Journal:  N Y State Dent J       Date:  2006 Mar-Apr

8.  Prevalence, neonatal characteristics, and first-year mortality of Down syndrome: a national study.

Authors:  Michel E Weijerman; A Marceline van Furth; Antonie Vonk Noordegraaf; Jacobus P van Wouwe; Chantal J M Broers; Reinoud J B J Gemke
Journal:  J Pediatr       Date:  2007-11-19       Impact factor: 4.406

9.  Dental anomalies in patients with Down syndrome.

Authors:  Mari Eli Leonelli de Moraes; Luiz Cesar de Moraes; Gustavo Nogara Dotto; Patrícia Pasquali Dotto; Luis Roque de Araújo dos Santos
Journal:  Braz Dent J       Date:  2007

10.  Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology.

Authors:  Sunjay Suri; Bryan D Tompson; Eshetu Atenafu
Journal:  Angle Orthod       Date:  2011-03       Impact factor: 2.079

View more
  2 in total

1.  Cis-acting: A pattern of lncRNAs for gene regulation in induced pluripotent stem cells from patients with Down syndrome determined by integrative analysis of lncRNA and mRNA profiling data.

Authors:  Wenbo Ma; Yanna Liu; Houshi Ma; Zhaorui Ren; Jingbin Yan
Journal:  Exp Ther Med       Date:  2021-05-02       Impact factor: 2.447

2.  Prevalence and Characteristics of Congenitally Missing Permanent Teeth among Orthodontic Patients in Southern Croatia.

Authors:  Jozo Badrov; Goran Gaspar; Antonija Tadin; Tea Galic; Danijela Kalibovic Govorko; Lidija Gavic; Robert Badrov; Ivan Galic
Journal:  Acta Stomatol Croat       Date:  2017-12
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.