Literature DB >> 26275592

Clinical and Histological Basis for the Use of Nasolabial Tissues in the Surgical Management of Oral Submucous Fibrosis.

Sonal B Shah1, David P Tauro2.   

Abstract

PURPOSE: The authors planned a clinical and histopathologic study to examine the behavior of nasolabial tissues (full-thickness skin flap) after being inset into the oral cavity for oral submucous fibrosis (OSMF) under the premise that skin that is foreign tissue to the oral cavity would be devoid of pathologic changes.
MATERIALS AND METHODS: Fourteen patients with OSMF and mouth openings with an interincisal distance shorter than 28 mm were included. The flap was evaluated clinically for 10 years, during which biopsy specimen was obtained from the mucocutaneous junction of the inset flap for histopathologic examination.
RESULTS: In this series, complications such as flap loss, infection, flap necrosis, obstructive sialadenitis, and damage to facial nerve branches were not observed. However, intraoral hair growth and extraoral scar at the donor site were seen in all patients, 3 of whom subsequently underwent scar revision. Histopathologically, the inset flap showed decreased keratinization and loss of adnexal structures. A mean mouth opening of 43.2 mm was achieved at 10 years postoperatively (mean increase, 24.4 mm). No relapse was encountered, even at the last follow-up.
CONCLUSION: The nasolabial island flap or any other full-thickness skin flap could be a viable and reliable option for reconstruction of intraoral defects from OSMF.
Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26275592     DOI: 10.1016/j.joms.2015.07.017

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  3 in total

1.  Surgical management of oral submucous fibrosis using buccal fat pad: a retrospective study of 30 cases.

Authors:  Himanshu Thukral; Sanjay Kumar Roy Chowdhury; Shakil Ahmed Nagori
Journal:  Oral Maxillofac Surg       Date:  2018-09-21

Review 2.  Complications in the use of bilateral inferiorly based nasolabial flaps for advanced oral submucous fibrosis.

Authors:  Rajesh Kshirsagar; Ajay Mohite; Suman Gupta; Amod Patankar; Vikrant Sane; Pratik Raut
Journal:  Natl J Maxillofac Surg       Date:  2016 Jul-Dec

Review 3.  Research Achievements of Oral Submucous Fibrosis: Progress and Prospect.

Authors:  Hui Xu; Feng-Yuan Lyu; Jiang-Yuan Song; Yu-Ming Xu; Er-Hui Jiang; Zheng-Jun Shang; Li-Li Chen; Zhi Xu
Journal:  Biomed Res Int       Date:  2021-03-18       Impact factor: 3.411

  3 in total

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