Literature DB >> 26275578

Assessment and delivery of treatment for hepatitis C virus infection in an opioid substitution treatment clinic with integrated peer-based support in Newcastle, Australia.

Julian Keats1, Michelle Micallef2, Jason Grebely3, Susan Hazelwood1, Hope Everingham4, Nikrant Shrestha4, Tracey Jones5, Nicky Bath6, Carla Treloar7, Gregory J Dore3, Adrian Dunlop8.   

Abstract

BACKGROUND: Among people who inject drugs (PWID), the prevalence of hepatitis C virus (HCV) infection is high; however HCV treatment uptake remains low. New models of care are needed to address the growing burden of HCV-related disease in PWID and to understand the barriers to assessment and treatment of HCV. This study evaluated assessment and treatment for HCV infection among PWID attending an opioid substitution treatment (OST) clinic with an integrated peer support worker model.
METHODS: Clients with a history of IDU and chronic HCV infection, attending the Newcastle Pharmacotherapy Service, Newcastle Australia, were recruited as part of a multisite prospective observational study (the ETHOS Cohort). Additional chart review was conducted for clients not enrolled in the ETHOS Cohort. A peer support worker was introduced to complement and extend services offered by the clinical team. Client contacts and assessments with a nurse and/or peer worker were evaluated, including those who commenced HCV treatment.
RESULTS: A total of 1447 clients attended the OST service during February 2009 and June 2014. Of these, 378 (26%) were assessed by a nurse and 242 (17%) by a clinician. HCV treatment was commenced by 20 (5%) participants and 15 (75%) achieved a sustained virological response (SVR). During May 2009 and July 2011, 332 nurse contacts and 726 peer worker contacts were evaluated. The nurse-led contacts were related to HCV treatment (50%) and review of pathology tests (34%), whereas peer worker contacts included discussion about HCV treatment (75%), education, counselling and/or support (53%) and general discussion about HCV infection (59%).
CONCLUSION: These data demonstrate that peer support workers facilitate broader discussion about HCV treatment, education and/or support, allowing nurses to focus on HCV-related assessment and treatment. HCV treatment uptake was very low in this cohort, but SVR was high. The integration of peer support workers in treatment programs within OST clinics may address barriers to HCV care, but further studies are needed to assess their impact on assessment and treatment outcomes.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Community support; HCV; Peer-based support; People who inject drugs; Treatment

Mesh:

Year:  2015        PMID: 26275578     DOI: 10.1016/j.drugpo.2015.07.006

Source DB:  PubMed          Journal:  Int J Drug Policy        ISSN: 0955-3959


  12 in total

Review 1.  Integrated opioid substitution therapy and HIV care: a qualitative systematic review and synthesis of client and provider experiences.

Authors:  Andy Guise; Maureen Seguin; Gitau Mburu; Susie McLean; Pippa Grenfell; Zahed Islam; Sergii Filippovych; Happy Assan; Andrea Low; Peter Vickerman; Tim Rhodes
Journal:  AIDS Care       Date:  2017-03-10

Review 2.  Direct-acting antiviral agents for HCV infection affecting people who inject drugs.

Authors:  Jason Grebely; Behzad Hajarizadeh; Gregory J Dore
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-08-23       Impact factor: 46.802

Review 3.  Hepatitis C elimination among people who inject drugs: Challenges and recommendations for action within a health systems framework.

Authors:  Emma Day; Margaret Hellard; Carla Treloar; Julie Bruneau; Natasha K Martin; Anne Øvrehus; Olav Dalgard; Andrew Lloyd; John Dillon; Matt Hickman; Jude Byrne; Alain Litwin; Mojca Maticic; Philip Bruggmann; Havard Midgard; Brianna Norton; Stacey Trooskin; Jeffrey V Lazarus; Jason Grebely
Journal:  Liver Int       Date:  2018-09-22       Impact factor: 5.828

4.  Initiating HCV treatment with direct acting agents in opioid agonist treatment: When to start for people co-infected with HIV?

Authors:  Dimitra Panagiotoglou; Emanuel Krebs; Jeong Eun Min; Michelle Olding; Keith Ahamad; Lianping Ti; Julio S G Montaner; Bohdan Nosyk
Journal:  Int J Drug Policy       Date:  2017-06-01

Review 5.  Hepatitis C models of care: approaches to elimination.

Authors:  Mia J Biondi; Jordan J Feld
Journal:  Can Liver J       Date:  2020-06-04

6.  Recommendations for the management of hepatitis C virus infection among people who inject drugs.

Authors:  Jason Grebely; Geert Robaeys; Philip Bruggmann; Alessio Aghemo; Markus Backmund; Julie Bruneau; Jude Byrne; Olav Dalgard; Jordan J Feld; Margaret Hellard; Matthew Hickman; Achim Kautz; Alain Litwin; Andrew R Lloyd; Stefan Mauss; Maria Prins; Tracy Swan; Martin Schaefer; Lynn E Taylor; Gregory J Dore
Journal:  Int J Drug Policy       Date:  2015-07-17

7.  Improving engagement with healthcare in hepatitis C: a randomised controlled trial of a peer support intervention.

Authors:  Helen R Stagg; Julian Surey; Marie Francis; Jennifer MacLellan; Graham R Foster; André Charlett; Ibrahim Abubakar
Journal:  BMC Med       Date:  2019-04-01       Impact factor: 8.775

Review 8.  Urgent action to fight hepatitis C in people who inject drugs in Europe.

Authors:  John F Dillon; Jeffrey V Lazarus; Homie A Razavi
Journal:  Hepatol Med Policy       Date:  2016-06-30

9.  Perceived benefits of the hepatitis C peer educators: a qualitative investigation.

Authors:  A W Batchelder; L Cockerham-Colas; D Peyser; S P Reynoso; I Soloway; A H Litwin
Journal:  Harm Reduct J       Date:  2017-09-29

10.  From client to co-worker: a case study of the transition to peer work within a multi-disciplinary hepatitis c treatment team in Toronto, Canada.

Authors:  Paula Tookey; Kate Mason; Jennifer Broad; Marty Behm; Lise Bondy; Jeff Powis
Journal:  Harm Reduct J       Date:  2018-08-14
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