Literature DB >> 26274799

Antiplatelet therapies for secondary stroke prevention: an update on clinical and cost-effectiveness.

Julia M Rothlisberger1, Bruce Ovbiagele1.   

Abstract

Stroke exacts a huge toll physically, mentally and economically. Antiplatelet therapy is the cornerstone of secondary stroke prevention, and proven drugs available to successfully realize this therapeutic strategy for the long term include aspirin, dipyridamole plus aspirin and clopidogrel. However, government agencies, corporations, health plans and patients desire more information about the clinical- and cost-effectiveness of these established therapies in real-world settings. This paper provides an update on evidence-based secondary stroke prevention with antiplatelet medications, discusses cost-related issues and offers perspective about the future.

Entities:  

Keywords:  antiplatelet; antithrombotics; cost; outcomes; prevention; stroke

Mesh：

Substances：

Year:  2015        PMID： 26274799      PMCID： PMC5549663          DOI： 10.2217/cer.15.22

Source DB:  PubMed          Journal:  J Comp Eff Res        ISSN： 2042-6305            Impact factor:   1.744


  38 in total

Review 1.  Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (review of Technology Appraisal No. 90): a systematic review and economic analysis.

Authors:  J Greenhalgh; A Bagust; A Boland; C Martin Saborido; J Oyee; M Blundell; Y Dundar; R Dickson; C Proudlove; M Fisher
Journal:  Health Technol Assess       Date:  2011-09       Impact factor: 4.014

2.  The CAPRIE trial: culmination of the preregistration program for clopidogrel. Clopidogrel versus aspirin in patients at risk of ischaemic events. Clopidogrel versus aspirin in patients at risk of ischaemic events.

Authors:  M Gent
Journal:  Semin Thromb Hemost       Date:  1999       Impact factor: 4.180

3.  Full coverage for preventive medications after myocardial infarction.

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Journal:  N Engl J Med       Date:  2011-11-14       Impact factor: 91.245

Review 4.  Singapore ministry of health clinical practice guidelines on stroke and transient ischemic attacks.

Authors:  N Venketasubramanian; K H Pwee; C P L Chen
Journal:  Int J Stroke       Date:  2011-06       Impact factor: 5.266

5.  A metaregression analysis of the dose-response effect of aspirin on stroke.

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Journal:  Arch Intern Med       Date:  1999-06-14

6.  Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement.

Authors:  Dirk Sibbing; Werner Koch; Daniela Gebhard; Tibor Schuster; Siegmund Braun; Julia Stegherr; Tanja Morath; Albert Schömig; Nicolas von Beckerath; Adnan Kastrati
Journal:  Circulation       Date:  2010-01-18       Impact factor: 29.690

7.  A comparison of two doses of aspirin (30 mg vs. 283 mg a day) in patients after a transient ischemic attack or minor ischemic stroke.

Authors:  Jan van Gijn; Ale Algra; Jaap Kappelle; Peter J Koudstaal; Anet van Latum
Journal:  N Engl J Med       Date:  1991-10-31       Impact factor: 91.245

8.  Efficacy and safety of vorapaxar in patients with prior ischemic stroke.

Authors:  David A Morrow; Mark J Alberts; Jay P Mohr; Sebastian F Ameriso; Marc P Bonaca; Shinya Goto; Graeme J Hankey; Sabina A Murphy; Benjamin M Scirica; Eugene Braunwald
Journal:  Stroke       Date:  2013-02-08       Impact factor: 7.914

9.  Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.

Authors:  H P Adams; B H Bendixen; L J Kappelle; J Biller; B B Love; D L Gordon; E E Marsh
Journal:  Stroke       Date:  1993-01       Impact factor: 7.914

10.  Statistical analysis plan for the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial.

Authors:  Philip M W Bath; Katie Robson; Lisa J Woodhouse; Nikola Sprigg; Robert Dineen; Stuart Pocock
Journal:  Int J Stroke       Date:  2014-12-30       Impact factor: 5.266
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  5 in total

1.  Comparison of the flexible parametric survival model and Cox model in estimating Markov transition probabilities using real-world data.

Authors:  Xudong Du; Mier Li; Ping Zhu; Ju Wang; Lisha Hou; Jijie Li; Hongdao Meng; Muke Zhou; Cairong Zhu
Journal:  PLoS One       Date:  2018-08-22       Impact factor: 3.240

Review 2.  Stroke in SARS-CoV-2 Infection: A Pictorial Overview of the Pathoetiology.

Authors:  Saeideh Aghayari Sheikh Neshin; Shima Shahjouei; Eric Koza; Isabel Friedenberg; Faezeh Khodadadi; Mirna Sabra; Firas Kobeissy; Saeed Ansari; Georgios Tsivgoulis; Jiang Li; Vida Abedi; Donna M Wolk; Ramin Zand
Journal:  Front Cardiovasc Med       Date:  2021-03-29

3.  Cost-effectiveness of short-protocol emergency brain MRI after negative non-contrast CT for minor stroke detection.

Authors:  Daniel Puhr-Westerheide; Matthias F Froelich; Olga Solyanik; Eva Gresser; Paul Reidler; Matthias P Fabritius; Matthias Klein; Konstantin Dimitriadis; Jens Ricke; Clemens C Cyran; Wolfgang G Kunz; Philipp M Kazmierczak
Journal:  Eur Radiol       Date:  2021-08-28       Impact factor: 5.315

Review 4.  Intracranial Arterial Calcifications: Potential Biomarkers of Stroke Risk and Outcome.

Authors:  Gianna M Fote; Sophia Raefsky; Kelton Mock; Amit Chaudhari; Mohammad Shafie; Wengui Yu
Journal:  Front Neurol       Date:  2022-09-01       Impact factor: 4.086

5.  Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia.

Authors:  Alejandro Roman-Gonzalez; Carlos Andrés Naranjo; Walter D Cardona-Maya; Dionis Vallejo; Francisco Garcia; Cesar Franco; Leonor Alvarez; Luis Ignacio Tobón; Marta Ibeth López; Carolina Rua; Gabriel Bedoya; Ángela Cadavid; José Domingo Torres
Journal:  Stroke Res Treat       Date:  2021-05-21
  5 in total

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