Literature DB >> 26273738

Beyond the flavour: a de-flavoured polyphenol rich extract of clove buds (Syzygium aromaticum L) as a novel dietary antioxidant ingredient.

Johannah NM1, Renny RM, Gopakumar G, Balu Maliakel, Sureshkumar D, Krishnakumar IM.   

Abstract

Though kitchen spices constitute an important source of dietary antioxidants, their consumption at a physiologically relevant dose is very often hampered by their unpleasant flavour characteristics. The present paper describes a novel approach to derive stable de-flavoured spice extracts with minimised taste and odour profiles which are suitable for impregnation into a variety of food and beverage matrices at physiologically relevant doses. A popular kitchen spice, clove bud (Syzygium aromaticum L), having strong flavour and pungency characteristics was selected in the present study to derive a de-flavoured extract with a standardised polyphenolic profile (Clovinol) and was incorporated into various foods. The antioxidant efficacy of Clovinol on healthy human volunteers who check and answer official emails involving responsibility was investigated by analysing their endogenous antioxidant enzymes and the extent of lipid peroxidation upon consumption of Clovinol either as capsules or in a different food/beverage at 250 mg per serving per day for 30 days. It was observed that Clovinol can be conveniently incorporated in various food matrices without flavour issues and the consumption of such food/beverage items may support an effective detoxification process with an average elevation of 33 ± 3% in catalase, 66 ± 8% in SOD, 56 ± 5% in GPx and 167 ± 21% in GSH levels, and 81 ± 11% attenuation in membrane lipid peroxidation level.

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Year:  2015        PMID: 26273738     DOI: 10.1039/c5fo00682a

Source DB:  PubMed          Journal:  Food Funct        ISSN: 2042-6496            Impact factor:   5.396


  4 in total

1.  The inhibitory activity of herbal medicines on the keys enzymes and steps related to carbohydrate and lipid digestion.

Authors:  Weerachat Sompong; Nuttapat Muangngam; Artitaya Kongpatpharnich; Chadakarn Manacharoenlarp; Chanatkarn Amorworasin; Tanyawan Suantawee; Thavaree Thilavech; Sirichai Adisakwattana
Journal:  BMC Complement Altern Med       Date:  2016-11-04       Impact factor: 3.659

2.  Safety assessment of a standardized polyphenolic extract of clove buds: Subchronic toxicity and mutagenicity studies.

Authors:  Liju Vijayasteltar; Gopakumar Gopinathan Nair; Balu Maliakel; Ramadasan Kuttan; Krishnakumar I M
Journal:  Toxicol Rep       Date:  2016-04-08

3.  Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study.

Authors:  Ratheesh Mohan; Svenia Jose; Johannah Mulakkal; Darla Karpinsky-Semper; Andrew G Swick; I M Krishnakumar
Journal:  BMC Complement Altern Med       Date:  2019-05-07       Impact factor: 3.659

Review 4.  Syzygium aromaticum L. (Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological and Toxicological Activities.

Authors:  Gaber El-Saber Batiha; Luay M Alkazmi; Lamiaa G Wasef; Amany Magdy Beshbishy; Eman H Nadwa; Eman K Rashwan
Journal:  Biomolecules       Date:  2020-01-30
  4 in total

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