Literature DB >> 26272004

Objective and Subjective Outcomes Following Maxillomandibular Advancement Surgery for Treatment of Patients With Extremely Severe Obstructive Sleep Apnea (Apnea-Hypopnea Index >100).

Reginald H Goodday1, Susan E Bourque2, Pember B Edwards3.   

Abstract

PURPOSE: It is important for patients and treating clinicians to know whether maxillomandibular advancement (MMA) surgery is effective when treating patients with obstructive sleep apnea syndrome (OSAS) and an extremely high apnea-hypopnea index (AHI) score. The purpose of this study was to evaluate objective and subjective treatment outcomes after MMA surgery for the treatment of OSAS in patients with a preoperative AHI score higher than 100. PATIENTS AND METHODS: This retrospective study included all patients who underwent MMA surgery for OSAS by members of the Department of Oral and Maxillofacial Surgery, QEII Health Science Centre (Halifax, Nova Scotia, Canada) from November 1996 through February 2014. Objective data were available in the form of polysomnographs (PSGs) obtained before and a minimum of 6 months after surgery. Patients completed a self-administered questionnaire before and after surgery regarding snoring, witnessed apneas, continuous positive airway pressure (CPAP) use, daytime somnolence, and overall satisfaction.
RESULTS: Two hundred sixty-five patients had MMA surgery, of which 13 had pre- and postoperative PSGs. PSGs showed a mean preoperative AHI score of 117.9 and a mean postsurgical AHI score of 16.1 (P < .001). Pre- and postoperative questionnaires were available for 9 patients. After surgery, 7 patients denied having any daytime sleepiness and 2 patients reported minimal daytime sleepiness. The mean preoperative Epworth Sleepiness Scale score was 12.9 (standard deviation [SD], 5.5), whereas the postoperative mean score was 5.0 (SD, 4.1; P = .004). Before surgery, all 9 patients reported loud snoring and 8 reported witnessed apneas. After surgery, 2 patients reported minimal snoring and only 1 patient continued to have witnessed apneas. Six patients used CPAP preoperatively and only 1 patient continued to use CPAP after surgery.
CONCLUSIONS: The results of this study suggest that MMA surgery for treatment of extremely severe OSA can be a highly successful 1-stage surgery, which eliminates the use of CPAP, improves subjective outcomes, and considerably decreases the AHI score.
Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26272004     DOI: 10.1016/j.joms.2015.07.016

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  6 in total

1.  Maxillomandibular advancement for obstructive sleep apnea: a retrospective prognostic factor study for surgical response.

Authors:  Ning Zhou; Jean-Pierre T F Ho; Wouter P Visscher; Naichuan Su; Frank Lobbezoo; Jan de Lange
Journal:  Sleep Breath       Date:  2022-10-22       Impact factor: 2.655

2.  The consequences of living with a severe malocclusion: A review of the literature.

Authors:  Richard Leck; Ninu Paul; Sarah Rolland; David Birnie
Journal:  J Orthod       Date:  2021-09-06

3.  Mandibular Repositioning Device (MRD) and Obstructive Sleep Apnea Syndrome.

Authors:  Zoe Nicolaou
Journal:  Ann Maxillofac Surg       Date:  2019 Jul-Dec

4.  Impact of Bimaxillary Advancement Surgery on the Upper Airway and on Obstructive Sleep Apnea Syndrome: a Meta-Analysis.

Authors:  Carolina Rojo-Sanchis; José Manuel Almerich-Silla; Vanessa Paredes-Gallardo; José María Montiel-Company; Carlos Bellot-Arcís
Journal:  Sci Rep       Date:  2018-04-10       Impact factor: 4.379

5.  Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.

Authors:  David Kent; Jeffrey Stanley; R Nisha Aurora; Corinna G Levine; Daniel J Gottlieb; Matthew D Spann; Carlos A Torre; Katherine Green; Christopher G Harrod
Journal:  J Clin Sleep Med       Date:  2021-12-01       Impact factor: 4.062

6.  The effect of intermittent hypoxia and fecal microbiota of OSAS on genes associated with colorectal cancer.

Authors:  Jia Gao; Hailong Cao; Qiang Zhang; Bangmao Wang
Journal:  Sleep Breath       Date:  2020-10-07       Impact factor: 2.816

  6 in total

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