Literature DB >> 26270904

Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice.

Bingbing Hu1,2, Fengying Dai3, Zhanming Fan4, Guanghui Ma1, Qunwei Tang2, Xin Zhang1.   

Abstract

As nanotheranostics, Congo red/Rutin-MNPs combine the abilities of diagnosis and treatment of Alzheimer's disease (AD). The biocompatible nanotheranostics system based on iron oxide magnetic nanoparticles, with ultrasmall size and excellent magnetic properties, can specifically detect amyloid plaques by magnetic resonance imaging, realize targeted delivery of AD therapeutic agents, achieve drug controlled release by H2O2 response, and prevent oxidative stress.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Alzheimer's disease; H2O2-responsive; magnetic resonance imaging; nanotheranostics; therapy

Mesh：

Substances：

Year:  2015        PMID： 26270904     DOI： 10.1002/adma.201502227

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  24 in total

Review 1.  Therapeutic Strategies and Nano-Drug Delivery Applications in Management of Aging Alzheimer's Disease.

Authors:  Thuy Trang Nguyen; Tuong Kha Vo; Giau Van Vo
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Nanomaterial based drug delivery systems for the treatment of neurodegenerative diseases.

Authors:  Shima Masoudi Asil; Jyoti Ahlawat; Gileydis Guillama Barroso; Mahesh Narayan
Journal:  Biomater Sci       Date:  2020-07-08       Impact factor: 6.843

3.  Detection of β-Amyloid by Sialic Acid Coated Bovine Serum Albumin Magnetic Nanoparticles in a Mouse Model of Alzheimer's Disease.

Authors:  Seyedmehdi Hossaini Nasr; Hovig Kouyoumdjian; Christiane Mallett; Sherif Ramadan; David C Zhu; Erik M Shapiro; Xuefei Huang
Journal:  Small       Date:  2017-11-14       Impact factor: 13.281

Review 4.  Neurotheranostics as personalized medicines.

Authors:  Bhavesh D Kevadiya; Brendan M Ottemann; Midhun Ben Thomas; Insiya Mukadam; Saumya Nigam; JoEllyn McMillan; Santhi Gorantla; Tatiana K Bronich; Benson Edagwa; Howard E Gendelman
Journal:  Adv Drug Deliv Rev       Date:  2018-10-26       Impact factor: 15.470

5.  3D-Printable Oxygen- and Drug-Carrying Nanocomposite Hydrogels for Enhanced Cell Viability.

Authors:  Ravi Kumar; Nermin Seda Kehr
Journal:  Nanomaterials (Basel)       Date:  2022-04-11       Impact factor: 5.719

6.  Multifunctional peptide-assembled micelles for simultaneously reducing amyloid-β and reactive oxygen species.

Authors:  Li Lei; Zhifeng Zou; Jin Liu; Zhiai Xu; Ying Fu; Yang Tian; Wen Zhang
Journal:  Chem Sci       Date:  2021-04-13       Impact factor: 9.825

Review 7.  Surface Modification of Iron Oxide-Based Magnetic Nanoparticles for Cerebral Theranostics: Application and Prospection.

Authors:  Yanyue Wu; Zhiguo Lu; Yan Li; Jun Yang; Xin Zhang
Journal:  Nanomaterials (Basel)       Date:  2020-07-24       Impact factor: 5.076

8.  Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer's disease.

Authors:  Xiao-Ying Sun; Ling-Jie Li; Quan-Xiu Dong; Jie Zhu; Ya-Ru Huang; Sheng-Jie Hou; Xiao-Lin Yu; Rui-Tian Liu
Journal:  J Neuroinflammation       Date:  2021-06-11       Impact factor: 8.322

9.  Targeting T1 and T2 dual modality enhanced magnetic resonance imaging of tumor vascular endothelial cells based on peptides-conjugated manganese ferrite nanomicelles.

Authors:  Mingfu Gong; Hua Yang; Song Zhang; Yan Yang; Dong Zhang; Zhaohui Li; Liguang Zou
Journal:  Int J Nanomedicine       Date:  2016-08-19

10.  A self-destructive nanosweeper that captures and clears amyloid β-peptides.

Authors:  Qiang Luo; Yao-Xin Lin; Pei-Pei Yang; Yi Wang; Guo-Bin Qi; Zeng-Ying Qiao; Bing-Nan Li; Kuo Zhang; Jing-Ping Zhang; Lei Wang; Hao Wang
Journal:  Nat Commun       Date:  2018-05-04       Impact factor: 14.919
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