| Literature DB >> 26269946 |
Giel P Göertz1, Gorben P Pijlman2.
Abstract
Dengue virus RNA is trimmed by the 5'→3' exoribonuclease XRN1 to produce an abundant, non-coding subgenomic flavivirus RNA (sfRNA) in infected cells. In a recent paper in Science, Manokaran et al. (2015) report that sfRNA binds TRIM25 to evade innate immune sensing of viral RNA by RIG-I.Entities:
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Year: 2015 PMID： 26269946 DOI： 10.1016/j.chom.2015.07.009
Source DB: PubMed Journal: Cell Host Microbe ISSN： 1931-3128 Impact factor: 21.023