Literature DB >> 26269465

Adverse Health Effects of Benzene Exposure Among Children Following a Flaring Incident at the British Petroleum Refinery in Texas City.

Mark A D'Andrea1, G Kesava Reddy2.   

Abstract

This study examined the health effects of benzene exposure among children from a flaring incident at the British Petroleum (BP) refinery in Texas City, Texas. A total of 899 children (benzene exposed, n = 641 and unexposed, n = 258), aged <17 years, were included. Hematological analysis showed that white blood cell (×10(3)/µL) counts were significantly decreased in the exposed children compared with the unexposed children (7.1 ± 2.2 versus 7.6 ± 2.1, P = .001). Similarly, the hemoglobin (g/dL) levels were decreased significantly in the exposed group compared with the unexposed group (12.7 ± 1.3 vs 13.1 ± 1.5, P = .001). Conversely, platelet (×10(3)/µL) counts were increased significantly in the exposed group compared with the unexposed group (318.6 ± 79.8 versus 266.9 ± 58.8, P = .001). Hepatic enzymes were also significantly elevated among exposed children compared with the unexposed children. These findings suggest that children exposed to benzene are at a higher risk of developing both hepatic and bone marrow-related disorders.
© The Author(s) 2015.

Entities:  

Keywords:  benzene exposure; benzene poisoning; blood disorders; chemical exposure; health impact; hematological toxicity; hepatotoxicity; refinery exposure

Mesh:

Substances:

Year:  2015        PMID: 26269465     DOI: 10.1177/0009922815594358

Source DB:  PubMed          Journal:  Clin Pediatr (Phila)        ISSN: 0009-9228            Impact factor:   1.168


  4 in total

1.  Blood BTEXS and heavy metal levels are associated with liver injury and systemic inflammation in Gulf states residents.

Authors:  Emily J Werder; Juliane I Beier; Dale P Sandler; Keith C Falkner; Tyler Gripshover; Banrida Wahlang; Lawrence S Engel; Matthew C Cave
Journal:  Food Chem Toxicol       Date:  2020-03-20       Impact factor: 6.023

2.  Toxicant-associated steatohepatitis: à propos a case of benzene exposure.

Authors:  Daniel Benharroch; Boris Talalay
Journal:  Int Med Case Rep J       Date:  2017-03-06

3.  Evaluating Phenotypic and Transcriptomic Responses Induced by Low-Level VOCs in Zebrafish: Benzene as an Example.

Authors:  Chia-Chen Wu; Jessica R Blount; Alex Haimbaugh; Samantha Heldman; Jeremiah N Shields; Tracie R Baker
Journal:  Toxics       Date:  2022-06-27

4.  Health Risks Associated With Benzene Exposure in Children: A Systematic Review.

Authors:  Mark A D'Andrea; G Kesava Reddy
Journal:  Glob Pediatr Health       Date:  2018-08-17
  4 in total

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