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Literature DB >> 26269123

Pregnane X receptor expression in skin: the good and the bad.

Daniel D Bikle¹.

Abstract

Entities: Chemical

Keywords: 7,12-dimethylbenz(a)anthracene; aryl hydrocarbon receptor; cancer; drug metabolism; pregane X receptor

Mesh：

Substances：

Year: 2015 PMID： 26269123 PMCID： PMC9000991 DOI： 10.1111/exd.12829

Source DB: PubMed Journal: Exp Dermatol ISSN： 0906-6705 Impact factor: 3.960

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References

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13 in total

1. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.

Authors: J Zhang; P Kuehl; E D Green; J W Touchman; P B Watkins; A Daly; S D Hall; P Maurel; M Relling; C Brimer; K Yasuda; S A Wrighton; M Hancock; R B Kim; S Strom; K Thummel; C G Russell; J R Hudson; E G Schuetz; M S Boguski
Journal: Pharmacogenetics Date: 2001-10

2. Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT).

Authors: David R Johnson; Chia-Wei Li; Liuh-Yow Chen; Jagadish C Ghosh; J Don Chen
Journal: Mol Pharmacol Date: 2005-10-11 Impact factor: 4.436

Pregnane X receptor expression in skin: the good and the bad.

1. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.

2. Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT).

Review 3. Cytochrome P-450 3A4: regulation and role in drug metabolism.

Review 4. Functional evolution of the pregnane X receptor.

Review 5. The aryl hydrocarbon receptor in barrier organ physiology, immunology, and toxicology.

Review 6. PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.

Review 7. Role of pregnane X receptor in chemotherapeutic treatment.

Review 8. Functions of the aryl hydrocarbon receptor in the skin.

9. Vitamin D receptor mediates DNA repair and is UV inducible in intact epidermis but not in cultured keratinocytes.

10. Persistence of skin-resident memory T cells within an epidermal niche.