Guilherme de Andrade Gagheggi Ravanini1, Pedro Eder Portari Filho2, Renato Abrantes Luna3, Vinicius Almeida de Oliveira4. 1. Oncologic Surgeon of the Gaffreé and Guinle University Hospital, Rio de Janeiro.. guilhermeravanini@gmail.com. 2. General Surgeon, Professor of the Rio de Janeiro School of Medicine and Surgery, Chief of Surgery Department B of the Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro.. guilhermeravanini@gmail.com. 3. General Surgeon of the Hospital of the State Officials of Rio de Janeiro, Rio de Janeiro.. guilhermeravanini@gmail.com. 4. Graduate Student of Medicine, Federal University of the State of Rio de Janeiro -UNIRIO (Brazil).. guilhermeravanini@gmail.com.
Abstract
BACKGROUND: this study aims to assess the organic inflammatory response of the video laparoscopic cholecystectomy, with abbreviation of the preoperative fasting to 2h using a carbohydrate and protein enriched solution. METHODS: this is a randomized, prospective study with patients divided into the following 2 groups: group A, conventional fasting and group B, 2h abbreviated fasting with oral ingestion of a carbohydrate and protein solution. Serum glucose, insulin, interleukin 1, and TNF-α were mesasured before ingestion of the solution, during induction of anesthesia, and 4 h after the end of surgery. RESULTS: thirty-eight patients completed the study without presenting pulmonary complications associated with bronchoaspiration. The postoperative HOMA-IR variance was greater in group A (p = 0.001). CONCLUSION: the abbreviation of preoperative fasting for 2 h, using carbohydrate and protein enriched solutions, is safe, reduces insulin resistance, and does not increase the risk of bronchoaspiration. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
RCT Entities:
BACKGROUND: this study aims to assess the organic inflammatory response of the video laparoscopic cholecystectomy, with abbreviation of the preoperative fasting to 2h using a carbohydrate and protein enriched solution. METHODS: this is a randomized, prospective study with patients divided into the following 2 groups: group A, conventional fasting and group B, 2h abbreviated fasting with oral ingestion of a carbohydrate and protein solution. Serum glucose, insulin, interleukin 1, and TNF-α were mesasured before ingestion of the solution, during induction of anesthesia, and 4 h after the end of surgery. RESULTS: thirty-eight patients completed the study without presenting pulmonary complications associated with bronchoaspiration. The postoperative HOMA-IR variance was greater in group A (p = 0.001). CONCLUSION: the abbreviation of preoperative fasting for 2 h, using carbohydrate and protein enriched solutions, is safe, reduces insulin resistance, and does not increase the risk of bronchoaspiration. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.