Literature DB >> 26267531

Tumor Heterogeneity: Focus on the Leaves, the Trees, or the Forest?

Joel S Parker1, Charles M Perou2.   

Abstract

Molecular studies of intra-tumor heterogeneity (ITH) are revealing a large amount of DNA-based variation in many individual tumors. In a recent publication by Yates and colleagues, the ITH of breast tumors was examined and shown to have important implications for the development of resistant disease, metastasis, and clinical sequencing efforts.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26267531     DOI: 10.1016/j.ccell.2015.07.011

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  9 in total

1.  A Cross-Sectional Comparison of Druggable Mutations in Primary Tumors, Metastatic Tissue, Circulating Tumor Cells, and Cell-Free Circulating DNA in Patients with Metastatic Breast Cancer: The MIRROR Study Protocol.

Authors:  Milagros Gonzalez-Rivera; Antoni C Picornell; Enrique L Alvarez; Miguel Martin
Journal:  JMIR Res Protoc       Date:  2016-08-16

2.  Immunotheranostic Polymersomes Modularly Assembled from Tetrablock and Diblock Copolymers with Oxidation-Responsive Fluorescence.

Authors:  Fanfan Du; Yu-Gang Liu; Evan Alexander Scott
Journal:  Cell Mol Bioeng       Date:  2017-04-10       Impact factor: 2.321

3.  Precision Cancer Diagnostics: Tracking Genomic Evolution in Clinical Trials.

Authors:  Francisco Beca; Andrew H Beck
Journal:  PLoS Med       Date:  2016-12-06       Impact factor: 11.069

Review 4.  Cultured circulating tumor cells and their derived xenografts for personalized oncology.

Authors:  Ruoxiang Wang; Gina C Y Chu; Stefan Mrdenovic; Alagappan A Annamalai; Andrew E Hendifar; Nicholas N Nissen; James S Tomlinson; Michael Lewis; Nallasivam Palanisamy; Hsian-Rong Tseng; Edwin M Posadas; Michael R Freeman; Stephen J Pandol; Haiyen E Zhau; Leland W K Chung
Journal:  Asian J Urol       Date:  2016-08-25

Review 5.  Prognostic and clinicopathological significance of cyclin B expression in patients with breast cancer: A meta-analysis.

Authors:  Xi Sun; Guangyan Zhangyuan; Liang Shi; Ying Wang; Beicheng Sun; Qiang Ding
Journal:  Medicine (Baltimore)       Date:  2017-05       Impact factor: 1.889

6.  Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes.

Authors:  Neeraj Kumar; Dan Zhao; Dulal Bhaumik; Amit Sethi; Peter H Gann
Journal:  BMC Cancer       Date:  2019-03-08       Impact factor: 4.430

7.  Effects of rat bone marrow-derived mesenchymal stem cells on breast cancer cells with differing hormone receptor status.

Authors:  Ying Wang; Shan Shao; Minna Luo; Shangke Huang; Lu Feng; Na Yuan; Fang Wu; Chengxue Dang; Xinhan Zhao
Journal:  Oncol Lett       Date:  2017-10-03       Impact factor: 2.967

Review 8.  The Significance of Liquid Biopsy in Pancreatic Cancer.

Authors:  Zi-Hao Qi; Hua-Xiang Xu; Shi-Rong Zhang; Jin-Zhi Xu; Shuo Li; He-Li Gao; Wei Jin; Wen-Quan Wang; Chun-Tao Wu; Quan-Xing Ni; Xian-Jun Yu; Liang Liu
Journal:  J Cancer       Date:  2018-09-08       Impact factor: 4.207

9.  Unmet Clinical Need: Developing Prognostic Biomarkers and Precision Medicine to Forecast Early Tumor Relapse, Detect Chemo-Resistance and Improve Overall Survival in High-Risk Breast Cancer.

Authors:  Gagan Gupta; Caroline Dasom Lee; Mary L Guye; Robert E Van Sciver; Michael P Lee; Alex C Lafever; Anthony Pang; Angela M Tang-Tan; Janet S Winston; Billur Samli; Rick J Jansen; Richard A Hoefer; Amy H Tang
Journal:  Ann Breast Cancer Ther       Date:  2020-05-02
  9 in total

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