| Literature DB >> 26267530 |
Dmitry Gabrilovich1, Yulia Nefedova2.
Abstract
Myeloid-derived suppressor cells (MDSCs) play a major role in cancer. MDSC expansion is closely associated with tumor progression, but molecular mechanisms of this expansion remain poorly understood. In this issue of Cancer Cell, Strauss and colleagues describe the roles of the nuclear receptor ROR1C in the regulation of MDSC differentiation and expansion.Entities:
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Year: 2015 PMID: 26267530 PMCID: PMC4669045 DOI: 10.1016/j.ccell.2015.07.007
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743