| Literature DB >> 26266236 |
Vijayanirmala Subraman1, Muthukumar Thiyagarajan2, N Malathi3, Sharada T Rajan4.
Abstract
Osteopontin (OPN), a matrix extracellular glyco-phosphoprotein is found in various tissues such as epithelium lined tissues, kidney, bone and teeth .It is also detected in all body fluids including blood and breast milk. OPN plays role in a number of physiological and pathologic events such as cell adhesion, migration and cell survival, angiogenesis, apoptosis, inflammation and wound healing. This review summarizes the current data of the biological activities of OPN in the development of tumour, its progression and metastasis.Entities:
Keywords: Angiogenesis; Cell adhesion; Metastasis; Osteopontin
Year: 2015 PMID: 26266236 PMCID: PMC4525627 DOI: 10.7860/JCDR/2015/12872.6111
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X