Literature DB >> 26266228

Primary Malignant Mixed Germ Cell Tumour with Squamous Cell Carcinoma of the Mandible; A Rare Entity.

Saurabh Kumar1, Arun Paul1, Harshad Parmar2, Rabin Chacko3.   

Abstract

Germ cell Tumours (GCT) are neoplasm derived from germ cells. GCT usually occurs inside the gonads. Extragonadal GCT's are rare. Most common GCT associated with head and neck region are the teratomas. Of the few teratomas found in the head and neck, malignant transformation of a teratomatous element is very uncommon, and primary bone involvement within the head and neck is even rare. We present a case of primary malignant mixed germ cell Tumour involving the mandible, the present case presented malignant transformation of the epithelial component showing foci of squamous cell carcinoma within the GCT.

Entities:  

Keywords:  Extragonadal tumour; Mandible tumour; Paediatric malignancy; Teratoma

Year:  2015        PMID: 26266228      PMCID: PMC4525618          DOI: 10.7860/JCDR/2015/13699.6072

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  12 in total

1.  Multipoint imprinting analysis indicates a common precursor cell for gonadal and nongonadal pediatric germ cell tumors.

Authors:  D T Schneider; A E Schuster; M K Fritsch; J Hu; T Olson; S Lauer; U Göbel; E J Perlman
Journal:  Cancer Res       Date:  2001-10-01       Impact factor: 12.701

2.  Yolk sac tumor of the mandible.

Authors:  Derek M Steinbacher; Joseph Upton; Reza Rahbar; Nalton F Ferraro
Journal:  J Oral Maxillofac Surg       Date:  2008-01       Impact factor: 1.895

Review 3.  Contemporary management of postchemotherapy testis cancer.

Authors:  Siamak Daneshmand; Peter Albers; Sophie Dorothea Fosså; Axel Heidenreich; Christian Kollmannsberger; Susan Krege; Craig Nichols; Jan Oldenburg; Lori Wood
Journal:  Eur Urol       Date:  2012-08-20       Impact factor: 20.096

4.  Extragonadal germ cell tumors of the head and neck region: review of 16 cases.

Authors:  E E Lack
Journal:  Hum Pathol       Date:  1985-01       Impact factor: 3.466

5.  Germ cell neoplasms of head and neck soft tissues: a pathologic spectrum of teratomatous and endodermal sinus tumors.

Authors:  L P Dehner; A Mills; A Talerman; G F Billman; H F Krous; C E Platz
Journal:  Hum Pathol       Date:  1990-03       Impact factor: 3.466

6.  Pediatric squamous cell carcinoma arising in an alpha-fetoprotein-producing mature cystic teratoma of the mandible.

Authors:  Robert J Cabay; Suman Setty; Joel L Schwartz; Mike Yao; Mary Lou Schmidt; Sara C Gordon
Journal:  Pediatr Blood Cancer       Date:  2009-01       Impact factor: 3.167

7.  Endodermal sinus tumor (yolk sac tumor) of the orbit.

Authors:  C E Margo; R Folberg; L E Zimmerman; I A Sesterhenn
Journal:  Ophthalmology       Date:  1983-12       Impact factor: 12.079

Review 8.  Non-midline endodermal sinus tumor in the head and neck region: a case report.

Authors:  R Kebudi; I Ayan; E Darendeliler; L Ağaoğlu; M Kinay; V Olgaç; N Bilge
Journal:  Med Pediatr Oncol       Date:  1993

9.  Squamous cell carcinoma arising in a benign teratoma of the maxilla.

Authors:  J J Kuhn; S R Schoem; G R Warnock
Journal:  Otolaryngol Head Neck Surg       Date:  1996-03       Impact factor: 5.591

10.  Current management of testicular cancer.

Authors:  Yu Seob Shin; Hyung Jin Kim
Journal:  Korean J Urol       Date:  2013-01-18
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  1 in total

1.  Lymph node metastasis as the initial symptom of a germ cell tumor in an adult: A case report.

Authors:  Fang Guo; Hongbing Wang; Heshun Xia; Hongwei Shi; Peng Xu; Guoliang Pi
Journal:  Medicine (Baltimore)       Date:  2022-07-29       Impact factor: 1.817

  1 in total

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