An Atypical Case of POEMS Syndrome with an Osteolytic Bone Lesion.

POEMS syndrome is a rare multisystem disorder with an underlying plasma cell dyscrasia associated with Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy and Skin changes. Usually it is associated with sclerotic bone lesions. It usually manifests in 5(th)-6(th) decade of life with a mean survival period of eight years. We report an unusual case of a 28-year-old male diagnosed with POEMS syndrome and had a lytic bone lesion the in sternum.