Literature DB >> 26264500

Synthesis and biological evaluation of new symmetric curcumin derivatives.

Rajendran Sribalan1, Maruthan Kirubavathi1, Govindharaj Banuppriya1, Vediappen Padmini2.   

Abstract

A series of novel curcumin bisacetamides aiming of enriching their biological activities have been synthesized. The synthesized compounds were screened for their in vitro antioxidant, anti-inflammatory and cytotoxic activities. All the compounds exhibited potent to good anti-inflammatory, antioxidant and noteworthy cytotoxic activities.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Acetamides; Anti-inflammatory; Antioxidant; Curcumin; Cytotoxicity

Mesh：

Substances：

Year:  2015        PMID： 26264500     DOI： 10.1016/j.bmcl.2015.07.088

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Platelet-12 lipoxygenase targeting via a newly synthesized curcumin derivative radiolabeled with technetium-99m.

Authors:  Reem Ibrahim Al-Wabli; Tamer Mostafa Mohamed Hafez Sakr; Mohammed Abdou Khedr; Adly Abdallah Selim; Mohamed Abd El-Motaleb Abd El-Rahman; Wafaa Abdou Zaghary
Journal:  Chem Cent J       Date:  2016-11-28       Impact factor: 4.215

Review 2.  Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives - A review.

Authors:  Augustine Amalraj; Anitha Pius; Sreerag Gopi; Sreeraj Gopi
Journal:  J Tradit Complement Med       Date:  2016-06-15

3.  Influence of a curcumin derivative on hIAPP aggregation in the absence and presence of lipid membranes.

Authors:  Amit S Pithadia; Anirban Bhunia; Rajendran Sribalan; Vediappen Padmini; Carol A Fierke; Ayyalusamy Ramamoorthy
Journal:  Chem Commun (Camb)       Date:  2016-01-18       Impact factor: 6.222
  3 in total

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