| Literature DB >> 26264059 |
Marie-Hélène Canu1,2, Fabrice Fryziel3,4, Jean-Pierre Noel3,4, Vincent Tiffreau3,4,5, Marc Digumber4,5, Bruno Bastide3,4.
Abstract
Limb immobilization or confinement to bed results in a severe atrophy and weakness of lower leg muscles. Full recovery of muscle strength and physical function is rare and may impact the patient's outcome. Studies performed on rodents have demonstrated that the deleterious structural and functional adaptations which occur during muscle deconditioning can be counteracted through adequate physiological stimuli. Thus, based on this fundamental work, we developed a device that combines mechanical stimulation of proprioceptors located in the plantar sole and Achilles' tendon. The device is adapted to patients immobilized and confined to bed. Stimulations can be applied on muscle in passive state. The protocol is non-invasive and is well accepted by patients. This paper presents the technical features of the device, as well as preliminary results of the first clinical study. This device might allow considering new therapeutic strategies for prevention of atrophy in many pathologies.Entities:
Keywords: Biomedical engineering; Mechanical stimulation; Rehabilitation; Therapeutic use
Mesh:
Year: 2015 PMID: 26264059 DOI: 10.1007/s11517-015-1363-y
Source DB: PubMed Journal: Med Biol Eng Comput ISSN: 0140-0118 Impact factor: 2.602