G Ferron1, L Simon2, F Guyon3, O Glehen4, D Goere5, D Elias5, M Pocard6, L Gladieff7, J M Bereder8, C Brigand9, J M Classe10, J M Guilloit11, F Quenet12, K Abboud13, C Arvieux14, F Bibeau15, C De Chaisemartin16, D Delroeux17, S Durand-Fontanier18, N Goasguen19, L Gouthi20, B Heyd17, R Kianmanesh21, E Leblanc22, V Loi23, G Lorimier24, F Marchal25, P Mariani26, C Mariette27, P Meeus28, S Msika29, P Ortega-Deballon30, J Paineau10, D Pezet31, G Piessen27, N Pirro32, C Pomel33, J Porcheron13, G Pourcher34, P Rat30, J M Regimbeau35, C Sabbagh35, E Thibaudeau10, J J Torrent36, D Tougeron37, J J Tuech38, F Zinzindohoue39, P Lundberg4, F Herin40, L Villeneuve41. 1. Department of Surgical Oncology, Claudius Regaud Institute - IUCT, Toulouse, France. Electronic address: ferron.gwenael@iuct-oncopole.fr. 2. Department of Surgical Oncology, Claudius Regaud Institute - IUCT, Toulouse, France. 3. Department of Surgical Oncology, Bergonie Institute, Bordeaux, France. 4. Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France; EMR 3738, Lyon 1 University, Lyon, France. 5. Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France. 6. Surgical Oncologic & Digestive Unit, Lariboisière University Hospital, Paris, France; INSERM, U 965, Paris, France. 7. Department of Medical Oncology, Claudius Regaud Institute - IUCT, Toulouse, France. 8. Department of General Surgery, Archet 2 University Hospital, Nice, France. 9. Department of General Surgery, Hautepierre University Hospital, Strasbourg, France. 10. Department of Surgical Oncology, René Gauducheau Cancer Center, Nantes, France. 11. Department of Surgical Oncology, Francois Baclesse Comprehensive Cancer Center, Caen, France. 12. Department of Surgical Oncology, Val d'Aurelle Montpellier Cancer Center, Montpellier, France. 13. Department of Digestive Surgery, University Hospital of Saint Etienne, Saint Etienne, France. 14. Department of Digestive Surgery, Michallon University Hospital, Grenoble, France. 15. Department of Pathology, Val d'Aurelle Montpellier Cancer Center, Montpellier, France. 16. Department of Surgical Oncology, Paoli-Calmettes Institute, Marseille, France. 17. Department of Digestive Surgery, Jean Minjoz University Hospital, Besançon, France. 18. Department of Visceral Surgery and Transplantation, Dupuytren University Hospital, Limoges, France. 19. Department of General Surgery, Diaconesses Croix Saint Simon Group Hospital, Paris, France. 20. Department of Digestive Surgery, Purpan University Hospital, Toulouse, France. 21. Department of Digestive Surgery, Robert Debré University Hospital, Reims, France. 22. Department of Gynaecological Surgery, Oscar Lambret Cancer Center, Lille, France. 23. Department of Digestive Surgery, Tenon University Hospital, Paris, France. 24. Department of Surgical Oncology, Paul Papin Cancer Center, Angers, France. 25. Department of Surgical Oncology, Lorraine Institute of Oncology, Vandoeuvre-les-Nancy, France. 26. Department of Surgical Oncology, Curie Institute, Paris, France. 27. Department of Digestive and Oncological Surgery, Claude-Huriez University Hospital, Lille, France. 28. Department of Surgery, Léon Bérard Comprehensive Cancer Center, Lyon, France. 29. Department of Surgery, Louis Mourier University Hospital, Colombes, France. 30. Department of Digestive Surgical Oncology, University Hospital of Dijon, Dijon, France. 31. Department of Digestive Surgery, Estaing University Hospital, Clermont-Ferrand, France. 32. Department of Digestive Surgery, Timône University Hospital, Marseille, France. 33. Department of Surgical Oncology, Jean Perrin Comprehensive Cancer Center, Clermont-Ferrand, France. 34. Department of General Surgery, Antoine-Béclère University Hospital, Clamart, France. 35. Department of Digestive Surgery, University Hospital of Amiens, Amiens, France. 36. Department of Gynecology, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain. 37. Department of Hepato-Gastroenterology, University Hospital, Poitiers, France. 38. Department of Digestive Surgery, Charles Nicolle University Hospital, Rouen, France. 39. Department of Digestive and General Surgery, G. Pompidou European Hospital, Paris, France. 40. Department of Occupational Medicine, University Hospital, Toulouse, France. 41. Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de Recherche Clinique, Lyon, France.
Abstract
BACKGROUND: Over the last two decades, many surgical teams have developed programs to treat peritoneal carcinomatosis with extensive cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). Currently, there are no specific recommendations for HIPEC procedures concerning environmental contamination risk management, personal protective equipment (PPE), or occupational health supervision. METHODS: A survey of the institutional practices among all French teams currently performing HIPEC procedures was carried out via the French network for the treatment of rare peritoneal malignancies (RENAPE). RESULTS: Thirty three surgical teams responded, 14 (42.4%) which reported more than 10 years of HIPEC experience. Some practices were widespread, such as using HIPEC machine approved by the European Community (100%), individualized or centralized smoke evacuation (81.8%), "open" abdominal coverage during perfusion (75.8%), and maintaining the same surgeon throughout the procedure (69.7%). Others were more heterogeneous, including laminar flow air circulation (54.5%) and the provision of safety protocols in the event of perfusate spills (51.5%). The use of specialized personal protective equipment is ubiquitous (93.9%) but widely variable between programs. CONCLUSION: Protocols regarding cytoreductive surgery/HIPEC and the associated professional risks in France lack standardization and should be established.
BACKGROUND: Over the last two decades, many surgical teams have developed programs to treat peritoneal carcinomatosis with extensive cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). Currently, there are no specific recommendations for HIPEC procedures concerning environmental contamination risk management, personal protective equipment (PPE), or occupational health supervision. METHODS: A survey of the institutional practices among all French teams currently performing HIPEC procedures was carried out via the French network for the treatment of rare peritoneal malignancies (RENAPE). RESULTS: Thirty three surgical teams responded, 14 (42.4%) which reported more than 10 years of HIPEC experience. Some practices were widespread, such as using HIPEC machine approved by the European Community (100%), individualized or centralized smoke evacuation (81.8%), "open" abdominal coverage during perfusion (75.8%), and maintaining the same surgeon throughout the procedure (69.7%). Others were more heterogeneous, including laminar flow air circulation (54.5%) and the provision of safety protocols in the event of perfusate spills (51.5%). The use of specialized personal protective equipment is ubiquitous (93.9%) but widely variable between programs. CONCLUSION: Protocols regarding cytoreductive surgery/HIPEC and the associated professional risks in France lack standardization and should be established.
Authors: K-E Schenk; R Schierl; M Angele; A Burkhart-Reichl; G Glockzin; A Novotny; D Nowak Journal: Int Arch Occup Environ Health Date: 2016-05-03 Impact factor: 3.015
Authors: Daniel Clerc; Martin Hübner; K R Ashwin; S P Somashekhar; Beate Rau; Wim Ceelen; Wouter Willaert; Naoual Bakrin; Nathalie Laplace; Mohammed Al Hosni; Edgar Luis Garcia Lozcano; Sebastian Blaj; Pompiliu Piso; Andrea Di Giorgio; Giuseppe Vizzelli; Cécile Brigand; Jean-Baptiste Delhorme; Amandine Klipfel; Rami Archid; Giorgi Nadiradze; Marc A Reymond; Olivia Sgarbura Journal: Pleura Peritoneum Date: 2021-02-12