P A Le Page1, R Furtado1, M Hayward2, S Law2, A Tan2, S J Vivian3, H Van der Wall4, G L Falk1,2,3. 1. 1 Concord Repatriation General Hospital, NSW , Australia. 2. 2 University of Sydney, NSW , Australia. 3. 3 Sydney Heartburn Clinic, Lindfield, NSW , Australia. 4. 4 Concord Nuclear Imaging, NSW , Australia.
Abstract
INTRODUCTION: The surgical management of symptomatic giant hiatus hernia (GHH) aims to improve quality of life (QoL) and reduce the risk of life threatening complications. Previous reports are predominantly those with small sample sizes and short follow-up periods. The present study sought to assess a large cohort of patients for recurrence and QoL over a longer time period. METHODS: This was a follow-up study of a prospectively collected database of 455 consecutive patients. Primary repair of GHH was evaluated by endoscopy/barium meal for recurrence and a standardised symptom questionnaire for QoL. Recurrence was assessed for size, elapsed time, oesophagitis and symptoms. RESULTS:Objective and subjective review was achieved in 91.9% and 68.6% of patients. The median age was 69 years (range: 15-93 years) and 64% were female. Laparoscopic repair was completed in 95% (mesh in 6% and Collis gastroplasty in 7%). The 30-day mortality rate was 0.9%. The proportion of patients alive at five and ten years were 90% and 75% respectively. Postoperative QoL scores improved from a mean of 95 to 111 (p<0.01) and were stable over time (112 at 10 years). The overall recurrence rate was 35.6% (149/418) at 42 months; this was 11.5% (48/418) for hernias >2cm and 24.2% (101/418) for <2cm. The rate of new recurrence at 0-1 years was 13.7% (>2cm = 3.4%, <2cm = 10.3%), at 1-5 years it was 30.8% (>2cm = 9.5%, <2cm = 21.3%), at 5-10 years it was 40.1% (>2cm = 13.8%, <2cm = 26.3%) and at over 10 years it was 50.0% (>2cm = 25.0%, <2cm = 25.0%). Recurrence was associated with oesophagitis but not decreased QoL. Revision surgery was required in 4.8% of cases (14.8% with recurrence). There were no interval major GHH complications. CONCLUSIONS: Surgery has provided sustained QoL improvements irrespective of recurrence. Recurrence occurred progressively over ten years and may predispose to oesophagitis.
RCT Entities:
INTRODUCTION: The surgical management of symptomatic giant hiatus hernia (GHH) aims to improve quality of life (QoL) and reduce the risk of life threatening complications. Previous reports are predominantly those with small sample sizes and short follow-up periods. The present study sought to assess a large cohort of patients for recurrence and QoL over a longer time period. METHODS: This was a follow-up study of a prospectively collected database of 455 consecutive patients. Primary repair of GHH was evaluated by endoscopy/barium meal for recurrence and a standardised symptom questionnaire for QoL. Recurrence was assessed for size, elapsed time, oesophagitis and symptoms. RESULTS: Objective and subjective review was achieved in 91.9% and 68.6% of patients. The median age was 69 years (range: 15-93 years) and 64% were female. Laparoscopic repair was completed in 95% (mesh in 6% and Collis gastroplasty in 7%). The 30-day mortality rate was 0.9%. The proportion of patients alive at five and ten years were 90% and 75% respectively. Postoperative QoL scores improved from a mean of 95 to 111 (p<0.01) and were stable over time (112 at 10 years). The overall recurrence rate was 35.6% (149/418) at 42 months; this was 11.5% (48/418) for hernias >2cm and 24.2% (101/418) for <2cm. The rate of new recurrence at 0-1 years was 13.7% (>2cm = 3.4%, <2cm = 10.3%), at 1-5 years it was 30.8% (>2cm = 9.5%, <2cm = 21.3%), at 5-10 years it was 40.1% (>2cm = 13.8%, <2cm = 26.3%) and at over 10 years it was 50.0% (>2cm = 25.0%, <2cm = 25.0%). Recurrence was associated with oesophagitis but not decreased QoL. Revision surgery was required in 4.8% of cases (14.8% with recurrence). There were no interval major GHH complications. CONCLUSIONS: Surgery has provided sustained QoL improvements irrespective of recurrence. Recurrence occurred progressively over ten years and may predispose to oesophagitis.
Entities:
Keywords:
Fundoplication; Gastro-oesophageal reflux; Hiatal hernia; Laparoscopy; Patient outcome assessment; Quality of life
Authors: Philip W Carrott; Jean Hong; Madhankumar Kuppusamy; Steven Kirtland; Richard P Koehler; Donald E Low Journal: J Thorac Cardiovasc Surg Date: 2011-11-20 Impact factor: 5.209
Authors: Sergio Diaz; L Michael Brunt; Mary E Klingensmith; Peggy M Frisella; Nathaniel J Soper Journal: J Gastrointest Surg Date: 2003-01 Impact factor: 3.452
Authors: E Eypasch; J I Williams; S Wood-Dauphinee; B M Ure; C Schmülling; E Neugebauer; H Troidl Journal: Br J Surg Date: 1995-02 Impact factor: 6.939
Authors: David S Liu; Chek Tog; Hou K Lim; Peter Stiven; Sarah K Thompson; David I Watson; Ahmad Aly Journal: World J Surg Date: 2018-06 Impact factor: 3.352
Authors: K E Blake; S J Zolin; C Tu; K F Baier; L R Beffa; D Alaedeen; D M Krpata; A S Prabhu; M J Rosen; C C Petro Journal: Trials Date: 2022-07-30 Impact factor: 2.728