Literature DB >> 26262248

Clinical Decision Support to Implement CYP2D6 Drug-Gene Interaction.

Pedro J Caraballo1, Mark Parkulo1, David Blair1, Michelle Elliott1, Cloann Schultz1, Joseph Sutton1, Padma Rao1, Jamie Bruflat1, Robert Bleimeyer1, John Crooks1, Donald Gabrielson1, Wayne Nicholson1, Carolyn Rohrer Vitek1, Kelly Wix1, Suzette J Bielinski1, Jyotishman Pathak1, Iftikhar Kullo1.   

Abstract

The level of CYP2D6 metabolic activity can be predicted by pharmacogenomic testing, and concomitant use of clinical decision support has the potential to prevent adverse effects from those drugs metabolized by this enzyme. Our initial findings after implementation of clinical decision support alerts integrated in the electronic health records suggest high feasibility, but also identify important challenges.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26262248

Source DB:  PubMed          Journal:  Stud Health Technol Inform        ISSN： 0926-9630


  3 in total

1.  Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol (RIGHT Protocol).

Authors:  Suzette J Bielinski; Jennifer L St Sauver; Janet E Olson; Nicholas B Larson; John L Black; Steven E Scherer; Matthew E Bernard; Eric Boerwinkle; Bijan J Borah; Pedro J Caraballo; Timothy B Curry; HarshaVardhan Doddapaneni; Christine M Formea; Robert R Freimuth; Richard A Gibbs; Jyothsna Giri; Matthew A Hathcock; Jianhong Hu; Debra J Jacobson; Leila A Jones; Sara Kalla; Tyler H Koep; Viktoriya Korchina; Christie L Kovar; Sandra Lee; Hongfang Liu; Eric T Matey; Michaela E McGree; Tammy M McAllister; Ann M Moyer; Donna M Muzny; Wayne T Nicholson; Lance J Oyen; Xiang Qin; Ritika Raj; Véronique L Roger; Carolyn R Rohrer Vitek; Jason L Ross; Richard R Sharp; Paul Y Takahashi; Eric Venner; Kimberly Walker; Liwei Wang; Qiaoyan Wang; Jessica A Wright; Tsung-Jung Wu; Liewei Wang; Richard M Weinshilboum
Journal:  Int J Epidemiol       Date:  2020-02-01       Impact factor: 7.196

2.  A model-based cost-effectiveness analysis of pharmacogenomic panel testing in cardiovascular disease management: preemptive, reactive, or none?

Authors:  Ye Zhu; James P Moriarty; Kristi M Swanson; Paul Y Takahashi; Suzette J Bielinski; Richard Weinshilboum; Liewei Wang; Bijan J Borah
Journal:  Genet Med       Date:  2020-10-12       Impact factor: 8.822

3.  Assessment and improvement of HIV screening rates in a Midwest primary care practice using an electronic clinical decision support system: a quality improvement study.

Authors:  Jasmine R Marcelin; Eugene M Tan; Alberto Marcelin; Marianne Scheitel; Praveen Ramu; Ronald Hankey; Pritesh Keniya; Majken Wingo; Stacey A Rizza; Frederick North; Rajeev Chaudhry
Journal:  BMC Med Inform Decis Mak       Date:  2016-07-04       Impact factor: 2.796
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.