Literature DB >> 26261734

Antioxidants in liver health.

Sael Casas-Grajales1, Pablo Muriel1.   

Abstract

Liver diseases are a worldwide medical problem because the liver is the principal detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various compounds that produce free radicals (FR). However, antioxidants scavenge FR and maintain the oxidative/antioxidative balance in the liver. When the liver oxidative/antioxidative balance is disrupted, the state is termed oxidative stress. Oxidative stress leads to deleterious processes in the liver and produces liver diseases. Therefore, restoring antioxidants is essential to maintain homeostasis. One method of restoring antioxidants is to consume natural compounds with antioxidant capacity. The objective of this review is to provide information pertaining to various antioxidants found in food that have demonstrated utility in improving liver diseases.

Entities:  

Keywords:  Antioxidant; Coffee; Curcumin; Liver diseases; Naringenin; Oxidative stress; Quercetin; Resveratrol; Silymarin

Year:  2015        PMID: 26261734      PMCID: PMC4526841          DOI: 10.4292/wjgpt.v6.i3.59

Source DB:  PubMed          Journal:  World J Gastrointest Pharmacol Ther        ISSN: 2150-5349


  134 in total

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4.  Protective effects of resveratrol against acetaminophen-induced toxicity in mice.

Authors:  Göksel Sener; Hale Z Toklu; A Ozer Sehirli; Ayliz Velioğlu-Oğünç; Sule Cetinel; Nursal Gedik
Journal:  Hepatol Res       Date:  2006-04-03       Impact factor: 4.288

5.  Resolution of liver fibrosis in chronic CCl4 administration in the rat after discontinuation of treatment: effect of silymarin, silibinin, colchicine and trimethylcolchicinic acid.

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Journal:  Basic Clin Pharmacol Toxicol       Date:  2005-05       Impact factor: 4.080

Review 6.  Resveratrol bioavailability and toxicity in humans.

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7.  Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.

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Journal:  Toxicol Appl Pharmacol       Date:  2007-09-26       Impact factor: 4.219

8.  Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats.

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Authors:  M G Hertog; P C Hollman; M B Katan; D Kromhout
Journal:  Nutr Cancer       Date:  1993       Impact factor: 2.900

10.  Effect of simvastatin and naringenin coadministration on rat liver DNA fragmentation and cytochrome P450 activity: an in vivo and in vitro study.

Authors:  T K Motawi; Z A Teleb; N A El-Boghdady; S A Ibrahim
Journal:  J Physiol Biochem       Date:  2013-11-22       Impact factor: 4.158

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  25 in total

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Journal:  Life Sci       Date:  2019-03-16       Impact factor: 5.037

2.  Curcumin induces apoptotic cell death in human pancreatic cancer cells via the miR-340/XIAP signaling pathway.

Authors:  Deying Yang; Yutao Li; Deqin Zhao
Journal:  Oncol Lett       Date:  2017-06-06       Impact factor: 2.967

3.  Tartary buckwheat extract alleviates alcohol-induced acute and chronic liver injuries through the inhibition of oxidative stress and mitochondrial cell death pathway.

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Journal:  Am J Transl Res       Date:  2020-01-15       Impact factor: 4.060

4.  Clinical Significance of the Thioredoxin System and Thioredoxin-Domain-Containing Protein Family in Hepatocellular Carcinoma.

Authors:  Sang Yeon Cho; Sungha Kim; Mi-Ju Son; Woo Sun Rou; Seok Hyun Kim; Hyuk Soo Eun; Byung Seok Lee
Journal:  Dig Dis Sci       Date:  2018-10-04       Impact factor: 3.199

Review 5.  Neovascularization is a key feature of liver fibrosis progression: anti-angiogenesis as an innovative way of liver fibrosis treatment.

Authors:  Mariia Zadorozhna; Sante Di Gioia; Massimo Conese; Domenica Mangieri
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6.  Chemical composition and hepatoprotective effect of essential oil from Myrtus communis L. flowers against CCL4-induced acute hepatotoxicity in rats.

Authors:  Anis Ben Hsouna; Sabah Dhibi; Wissal Dhifi; Wissem Mnif; Hmed Ben Nasr; Najla Hfaiedh
Journal:  RSC Adv       Date:  2019-01-28       Impact factor: 4.036

7.  Entacapone is an Antioxidant More Potent than Vitamin C and Vitamin E for Scavenging of Hypochlorous Acid and Peroxynitrite, and the Inhibition of Oxidative Stress-Induced Cell Death.

Authors:  Aaron Y Chen; Jian-Ming Lü; Qizhi Yao; Changyi Chen
Journal:  Med Sci Monit       Date:  2016-03-01

8.  Amomum cardamomum L. ethyl acetate fraction protects against carbon tetrachloride-induced liver injury via an antioxidant mechanism in rats.

Authors:  Dong-Woo Lim; Hyuck Kim; Ju-Yeon Park; Jai-Eun Kim; Jin-Young Moon; Sun-Dong Park; Won-Hwan Park
Journal:  BMC Complement Altern Med       Date:  2016-05-31       Impact factor: 3.659

9.  Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH.

Authors:  Jorge Simón; Naroa Goikoetxea-Usandizaga; Marina Serrano-Maciá; David Fernández-Ramos; Diego Sáenz de Urturi; Jessica J Gruskos; Pablo Fernández-Tussy; Sofía Lachiondo-Ortega; Irene González-Recio; Rubén Rodríguez-Agudo; Virginia Gutiérrez-de-Juan; Begoña Rodríguez-Iruretagoyena; Marta Varela-Rey; Paula Gimenez-Mascarell; María Mercado-Gomez; Beatriz Gómez-Santos; Carmen Fernandez-Rodriguez; Fernando Lopitz-Otsoa; Maider Bizkarguenaga; Sibylle Dames; Ute Schaeper; Franz Martin; Guadalupe Sabio; Paula Iruzubieta; Javier Crespo; Patricia Aspichueta; Kevan H-Y Chu; Daniela Buccella; César Martín; Teresa Cardoso Delgado; Luis Alfonso Martínez-Cruz; María Luz Martínez-Chantar
Journal:  J Hepatol       Date:  2021-02-09       Impact factor: 25.083

Review 10.  HCV-Induced Oxidative Stress: Battlefield-Winning Strategy.

Authors:  Khadija Rebbani; Kyoko Tsukiyama-Kohara
Journal:  Oxid Med Cell Longev       Date:  2016-05-12       Impact factor: 6.543

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