Detlev Ganten1, Gregg Semenza2, Thomas Sommer3. 1. Charité-Universitätsmedizin, Charitéplatz 1, 10117, Berlin, Germany. jmmeic@mdc-berlin.de. 2. Institute for Cell Engineering, The Johns Hopkins University School of Medicine, 733 North Broadway, Baltimore, MD, 21205, USA. 3. Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle Straße 10, 13125, Berlin, Germany.