Literature DB >> 26260156

Promoting microbiology education through the iGEM synthetic biology competition.

Richard Kelwick1, Laura Bowater2, Kay H Yeoman3, Richard P Bowater4.   

Abstract

Synthetic biology has developed rapidly in the 21st century. It covers a range of scientific disciplines that incorporate principles from engineering to take advantage of and improve biological systems, often applied to specific problems. Methods important in this subject area include the systematic design and testing of biological systems and, here, we describe how synthetic biology projects frequently develop microbiology skills and education. Synthetic biology research has huge potential in biotechnology and medicine, which brings important ethical and moral issues to address, offering learning opportunities about the wider impact of microbiological research. Synthetic biology projects have developed into wide-ranging training and educational experiences through iGEM, the International Genetically Engineered Machines competition. Elements of the competition are judged against specific criteria and teams can win medals and prizes across several categories. Collaboration is an important element of iGEM, and all DNA constructs synthesized by iGEM teams are made available to all researchers through the Registry for Standard Biological Parts. An overview of microbiological developments in the iGEM competition is provided. This review is targeted at educators that focus on microbiology and synthetic biology, but will also be of value to undergraduate and postgraduate students with an interest in this exciting subject area. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Keywords:  bioethics; biotechnology; iGEM; microbiology education; synthetic biology; transferable skills

Mesh:

Year:  2015        PMID: 26260156     DOI: 10.1093/femsle/fnv129

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN: 0378-1097            Impact factor:   2.742


  9 in total

Review 1.  "Learning on a chip:" Microfluidics for formal and informal science education.

Authors:  Darius G Rackus; Ingmar H Riedel-Kruse; Nicole Pamme
Journal:  Biomicrofluidics       Date:  2019-07-09       Impact factor: 2.800

2.  Tracking the emergence of synthetic biology.

Authors:  Philip Shapira; Seokbeom Kwon; Jan Youtie
Journal:  Scientometrics       Date:  2017-07-01       Impact factor: 3.238

3.  Cellular reagents for diagnostics and synthetic biology.

Authors:  Sanchita Bhadra; Arti Pothukuchy; Raghav Shroff; Austin W Cole; Michelle Byrom; Jared W Ellefson; Jimmy D Gollihar; Andrew D Ellington
Journal:  PLoS One       Date:  2018-08-15       Impact factor: 3.240

Review 4.  Auxotrophy to Xeno-DNA: an exploration of combinatorial mechanisms for a high-fidelity biosafety system for synthetic biology applications.

Authors:  Christopher M Whitford; Saskia Dymek; Denise Kerkhoff; Camilla März; Olga Schmidt; Maximilian Edich; Julian Droste; Boas Pucker; Christian Rückert; Jörn Kalinowski
Journal:  J Biol Eng       Date:  2018-08-14       Impact factor: 4.355

Review 5.  Biological Materials: The Next Frontier for Cell-Free Synthetic Biology.

Authors:  Richard J R Kelwick; Alexander J Webb; Paul S Freemont
Journal:  Front Bioeng Biotechnol       Date:  2020-05-12

6.  Ten simple rules for building an enthusiastic iGEM team.

Authors:  Luis Garcia Morales; Niek H A Savelkoul; Zoë Robaey; Nico J Claassens; Raymond H J Staals; Robert W Smith
Journal:  PLoS Comput Biol       Date:  2022-03-04       Impact factor: 4.475

7.  Lessons from a breast cell annotation competition series for school pupils.

Authors:  Wenqi Lu; Islam M Miligy; Fayyaz Minhas; Young Saeng Park; David R J Snead; Emad A Rakha; Clare Verrill; Nasir Rajpoot
Journal:  Sci Rep       Date:  2022-05-12       Impact factor: 4.996

8.  Strategies for structuring interdisciplinary education in Systems Biology: an European perspective.

Authors:  Marija Cvijovic; Thomas Höfer; Jure Aćimović; Lilia Alberghina; Eivind Almaas; Daniela Besozzi; Anders Blomberg; Till Bretschneider; Marta Cascante; Olivier Collin; Pedro de Atauri; Cornelia Depner; Robert Dickinson; Maciej Dobrzynski; Christian Fleck; Jordi Garcia-Ojalvo; Didier Gonze; Jens Hahn; Heide Marie Hess; Susanne Hollmann; Marcus Krantz; Ursula Kummer; Torbjörn Lundh; Gifta Martial; Vítor Martins Dos Santos; Angela Mauer-Oberthür; Babette Regierer; Barbara Skene; Egils Stalidzans; Jörg Stelling; Bas Teusink; Christopher T Workman; Stefan Hohmann
Journal:  NPJ Syst Biol Appl       Date:  2016-05-26

9.  BioBits™ Bright: A fluorescent synthetic biology education kit.

Authors:  Jessica C Stark; Ally Huang; Peter Q Nguyen; Rachel S Dubner; Karen J Hsu; Thomas C Ferrante; Mary Anderson; Ada Kanapskyte; Quinn Mucha; Jessica S Packett; Palak Patel; Richa Patel; Deema Qaq; Tyler Zondor; Julie Burke; Thomas Martinez; Ashlee Miller-Berry; Aparna Puppala; Kara Reichert; Miriam Schmid; Lance Brand; Lander R Hill; Jemima F Chellaswamy; Nuhie Faheem; Suzanne Fetherling; Elissa Gong; Eddie Marie Gonzalzles; Teresa Granito; Jenna Koritsaris; Binh Nguyen; Sujud Ottman; Christina Palffy; Angela Patel; Sheila Skweres; Adriane Slaton; TaRhonda Woods; Nina Donghia; Keith Pardee; James J Collins; Michael C Jewett
Journal:  Sci Adv       Date:  2018-08-01       Impact factor: 14.136

  9 in total

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