C H Teirlinck1, P A J Luijsterburg2, J Dekker3, A M Bohnen2, J A N Verhaar4, M A Koopmanschap5, P P van Es2, B W Koes2, S M A Bierma-Zeinstra2. 1. Erasmus MC University Medical Center, Department of General Practice, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. Electronic address: c.teirlinck@erasmusmc.nl. 2. Erasmus MC University Medical Center, Department of General Practice, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. 3. VU University Medical Center, Department of Rehabilitation Medicine, EMGO+ Institute for Health and Care Research, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. 4. Erasmus MC University Medical Center, Department of Orthopedics, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. 5. Erasmus University Rotterdam, Department of Health Policy and Management, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.
Abstract
OBJECTIVE: To assess the effectiveness of exercise therapy added to general practitioner (GP) care compared with GP care alone, in patients with hip osteoarthritis (OA) during 12 months follow-up. METHODS: We performed a multi-center parallel pragmatic randomized controlled trial in 120 general practices in the Netherlands. 203 patients, aged ≥45 years, with a new episode of hip complaints, complying with the ACR criteria for hip OA were randomized to the intervention group (n = 101; GP care with additional exercise therapy) or the control group (n = 102; GP care only). GP care was given by patient's own GP. The intervention group received, in addition, a maximum of 12 exercise therapy sessions in the first 3 months and hereafter three booster sessions. Blinding was not possible. Primary outcomes were hip pain and hip-related function measured with the HOOS questionnaire (score 0-100). RESULTS: The overall estimates on hip pain and function during the 12-month follow-up showed no between-group difference (intention-to-treat). At 3-months follow-up there was a statistically significant between-group difference for HOOS pain -3.7 (95% CI: -7.3; -0.2), effect size -0.23 and HOOS function -5.3 (95% CI: -8.9; -1.6), effect size -0.31. No adverse events were reported. CONCLUSIONS: No differences were found during 12-months follow-up on pain and function. At 3-months follow-up, pain and function scores differed in favor of patients allocated to the additional exercise therapy compared with GP care alone. TRIAL REGISTRATION: The Netherlands Trial Registry NTR1462.
RCT Entities:
OBJECTIVE: To assess the effectiveness of exercise therapy added to general practitioner (GP) care compared with GP care alone, in patients with hip osteoarthritis (OA) during 12 months follow-up. METHODS: We performed a multi-center parallel pragmatic randomized controlled trial in 120 general practices in the Netherlands. 203 patients, aged ≥45 years, with a new episode of hip complaints, complying with the ACR criteria for hip OA were randomized to the intervention group (n = 101; GP care with additional exercise therapy) or the control group (n = 102; GP care only). GP care was given by patient's own GP. The intervention group received, in addition, a maximum of 12 exercise therapy sessions in the first 3 months and hereafter three booster sessions. Blinding was not possible. Primary outcomes were hip pain and hip-related function measured with the HOOS questionnaire (score 0-100). RESULTS: The overall estimates on hip pain and function during the 12-month follow-up showed no between-group difference (intention-to-treat). At 3-months follow-up there was a statistically significant between-group difference for HOOS pain -3.7 (95% CI: -7.3; -0.2), effect size -0.23 and HOOS function -5.3 (95% CI: -8.9; -1.6), effect size -0.31. No adverse events were reported. CONCLUSIONS: No differences were found during 12-months follow-up on pain and function. At 3-months follow-up, pain and function scores differed in favor of patients allocated to the additional exercise therapy compared with GP care alone. TRIAL REGISTRATION: The Netherlands Trial Registry NTR1462.
Authors: Inka Roesel; Benjamin Steinhilber; Peter Martus; Pia Janssen; Inga Krauss Journal: Int J Environ Res Public Health Date: 2021-08-07 Impact factor: 3.390
Authors: Dylan R Barrow; Lauren M Abbate; Max R Paquette; Jeffrey B Driban; Heather K Vincent; Connie Newman; Stephen P Messier; Kirsten R Ambrose; Sarah P Shultz Journal: BMC Musculoskelet Disord Date: 2019-12-20 Impact factor: 2.362
Authors: Carolien H Teirlinck; Arianne P Verhagen; Elja A E Reijneveld; Jos Runhaar; Marienke van Middelkoop; Leontien M van Ravesteyn; Lotte Hermsen; Ingrid B de Groot; Sita M A Bierma-Zeinstra Journal: Int J Environ Res Public Health Date: 2020-10-10 Impact factor: 3.390