| Literature DB >> 26254146 |
Mark Jelcic1, Philipp Niethammer2.
Abstract
Nevi harbor some of the same oncogene mutations that also drive malign melanoma. Further tumor promoting events are required to unleash their carcinogenic potential. Using zebrafish whose melanocytes overexpress an HRAS-oncogene, a new study reports that injury induces melanoma, possibly through recruitment of neutrophils that trigger proliferation of preneoplastic melanocytes.Entities:
Mesh：
Year: 2015 PMID： 26254146 PMCID： PMC4567386 DOI： 10.1016/j.it.2015.07.008
Source DB: PubMed Journal: Trends Immunol ISSN： 1471-4906 Impact factor: 16.687