Literature DB >> 26253199

Patient-Funded Trials: Opportunity or Liability?

Danielle Marie Wenner1, Jonathan Kimmelman2, Alex John London3.   

Abstract

Patient-funded trials (PFTs) are gaining traction as a means of accelerating clinical translation. However, such trials sidestep mechanisms that promote rigor, relevance, efficiency, and fairness. We recommend that funding bodies or research institutions establish mechanisms for merit review of patient-funded trials, and we offer some basic criteria for evaluating PFT protocols.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26253199     DOI: 10.1016/j.stem.2015.07.016

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  6 in total

Review 1.  Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics.

Authors:  Lilyana Amezcua; Flavia Nelson
Journal:  Neurotherapeutics       Date:  2017-10       Impact factor: 7.620

Review 2.  Ethical development of stem-cell-based interventions.

Authors:  Amanda MacPherson; Jonathan Kimmelman
Journal:  Nat Med       Date:  2019-07-03       Impact factor: 53.440

3.  Ethical issues concerning a pay-to-participate stem cell study.

Authors:  Leigh Turner; Jeremy Snyder
Journal:  Stem Cells Transl Med       Date:  2021-06       Impact factor: 6.940

4.  Acceptability of donor funding for clinical trials in the UK: a qualitative empirical ethics study using focus groups to elicit the views of research patient public involvement group members, research ethics committee chairs and clinical researchers.

Authors:  Kirstie Shearman; Alexander Masters; Dominic Nutt; Simon Bowman; Heather Draper
Journal:  BMJ Open       Date:  2022-06-17       Impact factor: 3.006

5.  Permitting patients to pay for participation in clinical trials: the advent of the P4 trial.

Authors:  David Shaw; Guido de Wert; Wybo Dondorp; David Townend; Gerard Bos; Michel van Gelder
Journal:  Med Health Care Philos       Date:  2017-06

Review 6.  Cell-based therapeutic strategies for multiple sclerosis.

Authors:  Neil J Scolding; Marcelo Pasquini; Stephen C Reingold; Jeffrey A Cohen
Journal:  Brain       Date:  2017-11-01       Impact factor: 13.501

  6 in total

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